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David Kobiler

Explore the profile of David Kobiler including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 343
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Recent Articles
11.
Levy H, Weiss S, Altboum Z, Schlomovitz J, Rothschild N, Glinert I, et al.
Microb Pathog . 2011 Oct; 52(1):55-60. PMID: 22020310
Bacillus anthracis secretes three major components, which assemble into two bipartite toxins: lethal toxin (LT), composed of lethal factor (LF) and protective antigen (PA) and edema toxin (ET), composed of...
12.
Levy H, Weiss S, Altboum Z, Schlomovitz J, Rothschild N, Blachinsky E, et al.
Microb Pathog . 2011 Jul; 51(5):345-51. PMID: 21791242
The major virulence factor of Bacillus anthracis is the tripartite anthrax toxin, comprising the protective antigen (PA), lethal factor (LF) and edema factor (EF). The LF of B. anthracis is...
13.
Koneru R, Kobiler D, Lehrer S, Li J, van Rooijen N, Banerjee D, et al.
Neurosci Lett . 2011 Jul; 501(3):148-51. PMID: 21782894
The inflammatory response following traumatic injury to the central nervous system (CNS) includes the infiltration of large numbers of macrophages. This response has been implicated in both ongoing tissue damage...
14.
Weiss S, Kobiler D, Levy H, Pass A, Ophir Y, Rothschild N, et al.
Antimicrob Agents Chemother . 2011 Jan; 55(4):1533-42. PMID: 21263056
Respiratory anthrax, in the absence of early antibiotic treatment, is a fatal disease. This study aimed to test the efficiency of antibiotic therapy in curing infected animals and those sick...
15.
Weiss S, Levy H, Fisher M, Kobiler D, Altboum Z
Innate Immun . 2009 Feb; 15(1):43-51. PMID: 19201824
The involvement of TLR2 receptor in the innate response to infection with Bacillus anthracis was investigated. We studied the response to virulent or attenuated Vollum strains in either in vitro...
16.
Kobiler D, Weiss S, Levy H, Fisher M, Mechaly A, Pass A, et al.
Infect Immun . 2006 Sep; 74(10):5871-6. PMID: 16988266
The most aggressive form of anthrax results from inhalation of airborne spores of Bacillus anthracis and usually progresses unnoticed in the early stages because of unspecific symptoms. The only reliable...
17.
Weiss S, Kobiler D, Levy H, Marcus H, Pass A, Rothschild N, et al.
Infect Immun . 2005 Dec; 74(1):394-8. PMID: 16368995
Correlates between immunological parameters and protection against Bacillus anthracis infection in animals vaccinated with protective antigen (PA)-based vaccines could provide surrogate markers to evaluate the putative protective efficiency of immunization...
18.
Glod J, Kobiler D, Noel M, Koneru R, Lehrer S, Medina D, et al.
Blood . 2005 Oct; 107(3):940-6. PMID: 16204319
Subpopulations of bone marrow-derived cells can be induced to assume a number of endothelial properties in vitro. However, their ability to form a functional vascular barrier has not been demonstrated....
19.
Levy H, Fisher M, Ariel N, Altboum Z, Kobiler D
FEMS Microbiol Lett . 2005 Feb; 244(1):199-205. PMID: 15727841
Classification and differentiation of Bacillus anthracis isolates by genetic markers play an important role in anthrax research. We used a PCR based method--Random Amplification of Polymorphic DNA (RAPD)--to identify genetic...
20.
Altboum Z, Gozes Y, Barnea A, Pass A, White M, Kobiler D
Infect Immun . 2002 Oct; 70(11):6231-41. PMID: 12379702
The efficiency of postexposure prophylaxis against Bacillus anthracis infection was tested in guinea pigs infected intranasally with either Vollum or strain ATCC 6605 spores (75 times the 50% lethal dose...