Elad Bar-David
Overview
Explore the profile of Elad Bar-David including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
394
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Recent Articles
1.
Sittner A, Bar-David E, Glinert I, Ben-Shmuel A, Schlomovitz J, Levy H, et al.
Pathogens
. 2024 Nov;
13(11).
PMID: 39599489
Anthrax is a fatal zoonotic disease caused by exposure to spores. The CDC's guidelines divide anthrax treatment into three categories according to disease progression: post-exposure prophylaxis (PEP), systemic, and systemic...
2.
Ben-Shmuel A, Glinert I, Sittner A, Bar-David E, Schlomovitz J, Levy H, et al.
Antimicrob Agents Chemother
. 2024 Apr;
68(6):e0161023.
PMID: 38687017
Efficient treatment of anthrax-related meningitis in patients poses a significant therapeutic challenge. Previously, we demonstrated in our anthrax meningitis rabbit model that ciprofloxacin treatment is ineffective with most of the...
3.
Boby M, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson M, et al.
Science
. 2023 Nov;
382(6671):eabo7201.
PMID: 37943932
We report the results of the COVID Moonshot, a fully open-science, crowdsourced, and structure-enabled drug discovery campaign targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease. We discovered...
4.
Weiss S, Waidha K, Rajendran S, Benharroch D, Khalilia J, Levy H, et al.
Int J Mol Sci
. 2023 May;
24(9).
PMID: 37176034
We have previously published research on the anti-viral properties of an alkaloid mixture extracted from , the major components of the partially purified mixture found by NMR analysis. These are...
5.
Glinert I, Bar-David E, Ben-Shmuel A, Sittner A, Puni R, Laredo S, et al.
PLoS One
. 2023 Feb;
18(2):e0281879.
PMID: 36795682
Bacillus anthracis overcomes host immune responses by producing capsule and secreting toxins. Production of these virulence factors in response to entering the host environment was shown to be regulated by...
6.
Slobodin B, Sehrawat U, Lev A, Hayat D, Zuckerman B, Fraticelli D, et al.
Nucleic Acids Res
. 2022 Jul;
50(14):8080-8092.
PMID: 35849342
Translation of SARS-CoV-2-encoded mRNAs by the host ribosomes is essential for its propagation. Following infection, the early expressed viral protein NSP1 binds the ribosome, represses translation, and induces mRNA degradation,...
7.
Madar-Balakirski N, Rosner A, Melamed S, Politi B, Steiner M, Tamir H, et al.
Arch Toxicol
. 2022 Jan;
96(3):859-875.
PMID: 35032184
rVSV-ΔG-SARS-CoV-2-S is a clinical stage (Phase 2) replication competent recombinant vaccine against SARS-CoV-2. To evaluate the safety profile of the vaccine, a series of non-clinical safety, immunogenicity and efficacy studies...
8.
Fisher M, Levy H, Fatelevich E, Afrimov Y, Ben-Shmuel A, Rosenfeld R, et al.
Microbiol Spectr
. 2021 Oct;
9(2):e0087021.
PMID: 34612689
The first case of SARS-CoV-2 was discovered in Israel in late February 2020. Three major outbreaks followed, resulting in over 800,000 cases and over 6,000 deaths by April 2021. Our...
9.
Shifman O, Aminov T, Aftalion M, Gur D, Cohen H, Bar-David E, et al.
Microorganisms
. 2021 Jun;
9(5).
PMID: 34068310
Rapid determination of bacterial antibiotic susceptibility is important for proper treatment of infections. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) has recently published guidelines for rapid antimicrobial susceptibility testing...
10.
Sittner A, Bar-David E, Glinert I, Ben-Shmuel A, Schlomovitz J, Levy H, et al.
Microb Pathog
. 2021 Apr;
155:104904.
PMID: 33930422
The poly- δ- d-glutamic acid capsule of Bacillus anthracis plays a major role in this bacterium pathogenicity. Capsule synthesis relies on a 5 gene operon; capB, C, A, D and...