David Kimelman
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Explore the profile of David Kimelman including associated specialties, affiliations and a list of published articles.
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71
Citations
2411
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Recent Articles
1.
Rostomily C, Lee H, Tresenrider A, Daza R, Mullen A, Shendure J, et al.
Zebrafish
. 2025 Mar;
PMID: 40040474
Zebrafish is an ideal system to study the effect(s) of chemical, genetic, and environmental perturbations on development due to their high fecundity and fast growth. Recently, single-cell sequencing has emerged...
2.
Stooke-Vaughan G, Kim S, Yen S, Son K, Banavar S, Giammona J, et al.
Nat Commun
. 2025 Feb;
16(1):1839.
PMID: 39984461
Shaping embryonic tissues requires spatiotemporal changes in genetic and signaling activity as well as in tissue mechanics. Studies linking specific molecular perturbations to changes in the tissue physical state remain...
3.
Qiu C, Martin B, Welsh I, Daza R, Le T, Huang X, et al.
Nature
. 2024 Feb;
626(8001):1084-1093.
PMID: 38355799
The house mouse (Mus musculus) is an exceptional model system, combining genetic tractability with close evolutionary affinity to humans. Mouse gestation lasts only 3 weeks, during which the genome orchestrates...
4.
Saunders L, Srivatsan S, Duran M, Dorrity M, Ewing B, Linbo T, et al.
Nature
. 2023 Nov;
623(7988):782-791.
PMID: 37968389
The maturation of single-cell transcriptomic technologies has facilitated the generation of comprehensive cellular atlases from whole embryos. A majority of these data, however, has been collected from wild-type embryos without...
5.
Dorrity M, Saunders L, Duran M, Srivatsan S, Barkan E, Jackson D, et al.
Cell
. 2023 Nov;
186(23):5015-5027.e12.
PMID: 37949057
Embryonic development is remarkably robust, but temperature stress can degrade its ability to generate animals with invariant anatomy. Phenotypes associated with environmental stress suggest that some cell types are more...
6.
Qiu C, Martin B, Welsh I, Daza R, Le T, Huang X, et al.
bioRxiv
. 2023 Apr;
PMID: 37066300
The house mouse, , is an exceptional model system, combining genetic tractability with close homology to human biology. Gestation in mouse development lasts just under three weeks, a period during...
7.
Ye Z, Braden C, Wills A, Kimelman D
Development
. 2021 Jun;
148(11).
PMID: 34061173
During early embryogenesis, the vertebrate embryo extends from anterior to posterior because of the progressive addition of cells from a posteriorly localized neuromesodermal progenitor (NMp) population. An autoregulatory loop between...
8.
Ye Z, Kimelman D
Development
. 2020 Nov;
147(22).
PMID: 33154036
The early vertebrate embryo extends from anterior to posterior due to the addition of neural and mesodermal cells from a neuromesodermal progenitor (NMp) population located at the most posterior end...
9.
Kimelman D
Zebrafish
. 2018 Sep;
15(6):648-651.
PMID: 30256732
In June 2018, I traveled to India to teach in a Tibetan Buddhist monastery under the auspices of the Emory-Tibet Science Initiative (ETSI), a program that brings aspects of science...
10.
Kimelman D, Smith N, Lai J, Stainier D
Elife
. 2017 Dec;
6.
PMID: 29283341
The vertebrate embryo undergoes a series of dramatic morphological changes as the body extends to form the complete anterior-posterior axis during the somite-forming stages. The molecular mechanisms regulating these complex...