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David Kilburn

Explore the profile of David Kilburn including associated specialties, affiliations and a list of published articles. Areas
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Citations 62
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Recent Articles
1.
Link J, Eng J, Pelz C, MacPherson-Hawthorne K, Worth P, Sivagnanam S, et al.
Nat Cancer . 2025 Jan; 6(1):123-144. PMID: 39789181
Patients with metastatic pancreatic ductal adenocarcinoma survive longer if disease spreads to the lung but not the liver. Here we generated overlapping, multi-omic datasets to identify molecular and cellular features...
2.
Kong B, Stommel J, Keck J, Kilburn D, Streblow A, Egger J, et al.
JCO Precis Oncol . 2024 Jun; 8:e2300686. PMID: 38905574
Case report of a HER2-expressed ovarian clear cell carcinoma with exceptional response to trastuzumab deruxtecan.
3.
Hernandez S, Lim R, Onur T, Dane M, Smith R, Wang K, et al.
Hum Mol Genet . 2022 Dec; 32(9):1483-1496. PMID: 36547263
Astrocytes and brain endothelial cells are components of the neurovascular unit that comprises the blood-brain barrier (BBB) and their dysfunction contributes to pathogenesis in Huntington's disease (HD). Defining the contribution...
4.
Smith R, Devlin K, Kilburn D, Gross S, Sudar D, Bucher E, et al.
J Vis Exp . 2019 Jun; (147). PMID: 31180341
Understanding the impact of the microenvironment on the phenotype of cells is a difficult problem due to the complex mixture of both soluble growth factors and matrix-associated proteins in the...
5.
Watson S, Dane M, Chin K, Tatarova Z, Liu M, Liby T, et al.
Cell Syst . 2018 Mar; 6(3):329-342.e6. PMID: 29550255
Extrinsic signals are implicated in breast cancer resistance to HER2-targeted tyrosine kinase inhibitors (TKIs). To examine how microenvironmental signals influence resistance, we monitored TKI-treated breast cancer cell lines grown on...