David Keeling
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Explore the profile of David Keeling including associated specialties, affiliations and a list of published articles.
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63
Citations
1374
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Recent Articles
1.
Collins M, Pehrson R, Grindebacke H, Leffler A, Ramnegard M, Rannikmae H, et al.
PLoS One
. 2025 Jan;
20(1):e0317090.
PMID: 39820614
Multiple genetic associations suggest a causative relationship between Th17-related genes coding for proteins, such as IL-17A, IL-23 and STAT3, and psoriasis. Further support for this link comes from the findings...
2.
Curtis K, Jahne M, Keeling D, Gonzalez R
Microb Risk Anal
. 2024 Dec;
27-28:100315.
PMID: 39669296
Host-associated fecal indicator measurements can be coupled with quantitative microbial risk assessment to develop risk-based thresholds for recreational use of potential sewage-contaminated waters. These assessments require information on the relative...
3.
Iyer K, Keeling D, Hall R
Bioengineering (Basel)
. 2024 Aug;
11(8).
PMID: 39199737
Wear simulation aims to assess wear rates and their dependence on factors like load, kinematics, temperature, and implant orientation. Despite its significance, there is a notable gap in research concerning...
4.
Gonzalez D, Keeling D, Thompson H, Larson A, Denby J, Curtis K, et al.
J Microbiol Methods
. 2020 Sep;
178:106068.
PMID: 32980335
Collection System Investigation Microbial Source Tracking (CSI-MST) is a novel, sensitive approach for identifying sewer infrastructure deficiencies using molecular markers. This method requires both a detailed understanding of collection and...
5.
Gonzalez R, Curtis K, Bivins A, Bibby K, Weir M, Yetka K, et al.
Water Res
. 2020 Aug;
186:116296.
PMID: 32841929
Wastewater-based epidemiology (WBE) has been used to analyze markers in wastewater treatment plant (WWTP) influent to characterize emerging chemicals, drug use patterns, or disease spread within communities. This approach can...
6.
Psallidas I, Backer V, Kuna P, Palmer R, Necander S, Aurell M, et al.
Am J Respir Crit Care Med
. 2020 Aug;
203(3):296-306.
PMID: 32809843
To examine the potential of TLR9 (Toll-like receptor 9) activation to modulate the type 2 immune response in asthma. To evaluate efficacy and safety of AZD1419, an inhaled TLR9 agonist,...
7.
Asimus S, Palmer R, Albayaty M, Forsman H, Lundin C, Olsson M, et al.
Br J Clin Pharmacol
. 2020 Feb;
86(7):1398-1405.
PMID: 32067249
Aims: Retinoic acid-related orphan receptor γ (RORγ), a master regulator of T-helper 17 (Th17) cell function and differentiation, is an attractive target for treatment of Th17-driven diseases. This first-in-human study...
8.
Bury L, Megy K, Stephens J, Grassi L, Greene D, Gleadall N, et al.
Hum Mutat
. 2019 Sep;
41(1):277-290.
PMID: 31562665
The heterogeneous manifestations of MYH9-related disorder (MYH9-RD), characterized by macrothrombocytopenia, Döhle-like inclusion bodies in leukocytes, bleeding of variable severity with, in some cases, ear, eye, kidney, and liver involvement, make...
9.
Willan J, Katz H, Keeling D
Br J Haematol
. 2019 Feb;
185(2):289-296.
PMID: 30727024
Artificial neural networks are machine-learning algorithms designed to analyse data without a pre-existing hypothesis as to any associations that may exist. This technique has not previously been applied to the...
10.