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Stephen Delaney

Explore the profile of Stephen Delaney including associated specialties, affiliations and a list of published articles. Areas
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Citations 56
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Recent Articles
1.
Postel S, Wissler L, Johansson C, Gunnarsson A, Gordon E, Collins B, et al.
Nat Struct Mol Biol . 2023 Feb; 30(3):286-295. PMID: 36747092
The glucocorticoid receptor (GR) is a ligand-activated transcription factor that binds DNA and assembles co-regulator complexes to regulate gene transcription. GR agonists are widely prescribed to people with inflammatory and...
2.
Monkley S, Krishnaswamy J, Goransson M, Clausen M, Meuller J, Thorn K, et al.
PLoS One . 2020 Dec; 15(12):e0243807. PMID: 33332401
Induced pluripotent stem cells (iPSC) offer the possibility to generate diverse disease-relevant cell types, from any genetic background with the use of cellular reprogramming and directed differentiation. This provides a...
3.
Psallidas I, Backer V, Kuna P, Palmer R, Necander S, Aurell M, et al.
Am J Respir Crit Care Med . 2020 Aug; 203(3):296-306. PMID: 32809843
To examine the potential of TLR9 (Toll-like receptor 9) activation to modulate the type 2 immune response in asthma. To evaluate efficacy and safety of AZD1419, an inhaled TLR9 agonist,...
4.
Jackson S, Candia A, Delaney S, Floettmann S, Wong C, Campbell J, et al.
Clin Pharmacol Ther . 2017 Nov; 104(2):335-345. PMID: 29134633
Current asthma treatments address symptoms rather than the underlying disease pathophysiology, a better understanding of which has led to the identification of the Th2 high endotype. The activation of Toll-like...
5.
Bell J, Dymond M, Biffen M, Delaney S, Keeling D, Zhang H, et al.
Toxicol Appl Pharmacol . 2017 Nov; 338:9-19. PMID: 29122671
AZD8848 is a TLR7 agonist antedrug developed for administration by inhalation dosing for the treatment of allergic diseases, such as asthma. Allergic asthma is associated with increased levels of Th2...
6.
Delaney S, Biffen M, Maltby J, Bell J, Asimus S, Aggarwal A, et al.
BMJ Open Respir Res . 2016 Mar; 3(1):e000113. PMID: 26933507
Background: Many patients with asthma have a T-helper type 2 (Th2) driven inflammation of the lung, whereas toll-like receptor 7 (TLR7) agonists, by inducing type I interferons, inhibit Th2 responses....
7.
Rivera J, Delaney S
Healthc Financ Manage . 2015 Dec; 69(2):64-7. PMID: 26665541
Orlando Health has brought its hospital and physician practice revenue cycle systems into better balance using four sets of customized analytics: Physician performance analytics gauge the total net revenue for...