David K Crossman
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Explore the profile of David K Crossman including associated specialties, affiliations and a list of published articles.
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144
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2998
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Recent Articles
11.
Slominski R, Kim T, Janjetovic Z, Brozyna A, Podgorska E, Dixon K, et al.
Cancers (Basel)
. 2024 Jun;
16(12).
PMID: 38927967
Melanoma, originating through malignant transformation of melanin-producing melanocytes, is a formidable malignancy, characterized by local invasiveness, recurrence, early metastasis, resistance to therapy, and a high mortality rate. This review discusses...
12.
Church C, Fay C, Kriukov E, Liu H, Cannon A, Baldwin L, et al.
Acta Neuropathol Commun
. 2024 Jun;
12(1):102.
PMID: 38907342
Neurofibromatosis Type 1 (NF1) is caused by loss of function variants in the NF1 gene. Most patients with NF1 develop skin lesions called cutaneous neurofibromas (cNFs). Currently the only approved...
13.
Hale A, Liu S, Huang F, Song Y, Crowley M, Crossman D, et al.
Neurosurgery
. 2024 May;
95(5):1082-1088.
PMID: 38747605
Background And Objectives: Vein of Galen malformation (VOGM), the result of arteriovenous shunting between choroidal and/or subependymal arteries and the embryologic prosencephalic vein, is among the most severe cerebrovascular disorders...
14.
Kundu A, Brinkley G, Nam H, Karki S, Kirkman R, Pandit M, et al.
J Clin Invest
. 2024 May;
134(13).
PMID: 38743486
Tumor cells are known to undergo considerable metabolic reprogramming to meet their unique demands and drive tumor growth. At the same time, this reprogramming may come at a cost with...
15.
Sothers H, Hu X, Crossman D, Si Y, Alexander M, McDonald M, et al.
bioRxiv
. 2024 May;
PMID: 38712206
Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive disease due to loss-of-function mutations in the gene. DMD-related skeletal muscle wasting is typified by an aberrant immune response involving upregulation...
16.
Yan C, Richard M, Gibson C, He J, Bosworth A, Crossman D, et al.
J Clin Oncol
. 2024 Apr;
42(20):2415-2424.
PMID: 38635938
Purpose: Therapy-related myeloid neoplasm (t-MN) is a life-threatening complication of autologous peripheral blood stem cell transplantation (aPBSCT) for Hodgkin lymphoma (HL). Although previous studies have reported an association between clonal...
17.
Sharafeldin N, Zhou L, Singh P, Crossman D, Wang X, Hageman L, et al.
JACC CardioOncol
. 2024 Jan;
5(6):807-818.
PMID: 38205005
Background: Anthracyclines are highly effective in treating cancer, albeit with increased cardiomyopathy risk. Although risk is attributed to associations with single nucleotide polymorphisms (SNPs), multiple SNPs on a gene and...
18.
Hawkins C, Jones A, Gordon E, Harsh Y, Ziebro J, Willey C, et al.
Cell Death Discov
. 2023 Dec;
9(1):451.
PMID: 38086808
Sphingolipid metabolism is dysregulated in many cancers, allowing cells to evade apoptosis through increased sphingosine-1-phosphate (S1P) and decreased ceramides. Ceramidases hydrolyze ceramides to sphingosine, which is phosphorylated by sphingosine kinases...
19.
Jin L, Chen Y, Muzaffar S, Li C, Mier-Aguilar C, Khan J, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(49):e2315096120.
PMID: 38011564
Hidradenitis suppurativa (HS) is a complex inflammatory skin disease with undefined mechanistic underpinnings. Here, we investigated HS epithelial cells and demonstrated that HS basal progenitors modulate their lineage restriction and...
20.
Srivastava R, Muzaffar S, Khan J, Crossman D, Agarwal A, Athar M
J Pharmacol Exp Ther
. 2023 Nov;
388(2):546-559.
PMID: 37914412
Vesicants such as arsenicals and mustards produce highly painful cutaneous inflammatory and blistering responses, hence developed as chemical weapons during World War I/II. Here, using lewisite and sulfur mustard surrogates,...