David H Lovett
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Explore the profile of David H Lovett including associated specialties, affiliations and a list of published articles.
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64
Citations
1363
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Recent Articles
1.
Liu H, Zask A, Forouhar F, Iketani S, Williams A, Vaz D, et al.
Nat Commun
. 2025 Jan;
16(1):152.
PMID: 39747827
Variants of SARS-CoV-2 have continued to emerge across the world and cause hundreds of deaths each week. Due to the limited efficacy of vaccines against SARS-CoV-2 and resistance to current...
2.
Grubbs V, Garcia F, Vittinghoff E, Jue B, Ryder M, Lovett D, et al.
Kidney Med
. 2020 Aug;
2(1):49-58.
PMID: 32734226
Rationale & Objective: Observational studies have suggested that periodontal disease may be a modifiable risk factor for chronic kidney disease (CKD). The Kidney and Periodontal Disease (KAPD) Study was designed...
3.
Spaulding K, Zhu Y, Takaba K, Ramasubramanian A, Badathala A, Haraldsson H, et al.
J Biomed Mater Res A
. 2020 Apr;
108(8):1736-1746.
PMID: 32270584
The decrease in contractility in myocardium adjacent (border zone; BZ) to a myocardial infarction (MI) is correlated with an increase in reactive oxygen species (ROS). We hypothesized that injection of...
4.
Lee H, Lee S, Lee M, Park M, Kim S, Shin N, et al.
PLoS One
. 2019 Aug;
14(8):e0221798.
PMID: 31461499
Background: Diabetic cardiomyopathy (DM CMP) is defined as cardiomyocyte damage and ventricular dysfunction directly associated with diabetes independent of concomitant coronary artery disease or hypertension. Matrix metalloproteinases (MMPs), especially MMP-2,...
5.
Cowley P, Wang G, Swigart P, Raghunathan A, Reddy N, Dulam P, et al.
Am J Physiol Heart Circ Physiol
. 2018 Nov;
316(1):H224-H232.
PMID: 30412439
Right ventricular (RV) failure (RVF) is a serious disease with no effective treatment available. We recently reported a disease prevention study showing that chronic stimulation of α-adrenergic receptors (α-ARs), started...
6.
Rhee H, Han M, Kim S, Kim I, Lee H, Bae S, et al.
Kidney Res Clin Pract
. 2018 Sep;
37(3):222-229.
PMID: 30254846
Background: This study was undertaken to explore the effects of aging on the kidneys in mouse models of diabetes and chronic kidney disease (CKD), and to compare the expression of...
7.
Kim I, Kim S, Lee H, Bae S, Ha H, Jung E, et al.
BMC Nephrol
. 2018 Sep;
19(1):248.
PMID: 30253743
Background: We recently reported on the enhanced tubular expression of two discrete isoforms of the MMP-2 (full length and N-terminal truncated, FL-MMP-2, NTT-MMP-2) in a murine model and human diabetic...
8.
Spaulding K, Takaba K, Collins A, Faraji F, Wang G, Aguayo E, et al.
PLoS One
. 2018 Feb;
13(2):e0192720.
PMID: 29432443
Decreased contractility in the non-ischemic border zone surrounding a MI is in part due to degradation of cardiomyocyte sarcomeric components by intracellular matrix metalloproteinase-2 (MMP-2). We recently reported that MMP-2...
9.
Cowley P, Wang G, Joshi S, Swigart P, Lovett D, Simpson P, et al.
Am J Physiol Heart Circ Physiol
. 2017 Aug;
313(6):H1109-H1118.
PMID: 28822963
Failure of the right ventricle (RV) is a serious disease with a poor prognosis and limited treatment options. Signaling by α-adrenergic receptors (α-ARs), in particular the α-subtype, mediate cardioprotective effects...
10.
Baligand C, Qin H, True-Yasaki A, Gordon J, von Morze C, DeLos Santos J, et al.
NMR Biomed
. 2017 Jul;
30(10).
PMID: 28708304
Acute kidney injury (AKI) is a major risk factor for the development of chronic kidney disease (CKD). Persistent oxidative stress and mitochondrial dysfunction are implicated across diverse forms of AKI...