David H Gutmann
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Explore the profile of David H Gutmann including associated specialties, affiliations and a list of published articles.
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18485
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Recent Articles
11.
Gutmann D
Neurooncol Adv
. 2024 Jun;
6(1):vdae054.
PMID: 38855054
Brain tumors are the leading cause of cancer-related death in children, where low-grade gliomas (LGGs) predominate. One common hereditary cause for LGGs involves neurofibromatosis-1 (NF1) gene mutation, as seen in...
12.
Pan Y, Hysinger J, Yalcin B, Lennon J, Byun Y, Raghavan P, et al.
Nat Neurosci
. 2024 May;
27(8):1555-1564.
PMID: 38816530
Neurogenetic disorders, such as neurofibromatosis type 1 (NF1), can cause cognitive and motor impairments, traditionally attributed to intrinsic neuronal defects such as disruption of synaptic function. Activity-regulated oligodendroglial plasticity also...
13.
OHare P, Cooney T, de Blank P, Gutmann D, Kieran M, Milde T, et al.
Neuro Oncol
. 2024 May;
26(8):1357-1366.
PMID: 38743009
Pediatric low-grade glioma (pLGG) is the most common childhood brain tumor group. The natural history, when curative resection is not possible, is one of a chronic disease with periods of...
14.
Kotch C, de Blank P, Gutmann D, Fisher M
Childs Nerv Syst
. 2024 May;
40(10):3241-3250.
PMID: 38704493
Neurofibromatosis type 1 (NF1) is an autosomal dominant cancer predisposition syndrome characterized by the development of both central and peripheral nervous system tumors. Low-grade glioma (LGG) is the most prevalent...
15.
Sandin S, Yip B, Yin W, Weiss L, Dougherty J, Fass S, et al.
JAMA Psychiatry
. 2024 Apr;
81(7):673-680.
PMID: 38630491
Importance: Autism spectrum disorder (ASD) is a neurodevelopmental disorder more prevalent in males than in females. The cause of ASD is largely genetic, but the association of genetics with the...
16.
Anastasaki C, Chatterjee J, Koleske J, Gao Y, Bozeman S, Kernan C, et al.
Neuro Oncol
. 2024 Apr;
26(8):1496-1508.
PMID: 38607967
Background: With the recognition that noncancerous cells function as critical regulators of brain tumor growth, we recently demonstrated that neurons drive low-grade glioma initiation and progression. Using mouse models of...
17.
Amit M, Anastasaki C, Dantzer R, Demir I, Deneen B, Dixon K, et al.
Cancer Discov
. 2024 Apr;
14(4):669-673.
PMID: 38571430
The field of cancer neuroscience has begun to define the contributions of nerves to cancer initiation and progression; here, we highlight the future directions of basic and translational cancer neuroscience...
18.
Kerashvili N, Gutmann D
Expert Rev Neurother
. 2024 Feb;
24(4):409-420.
PMID: 38406862
Introduction: Neurofibromatosis type 1 (NF1) is a rare neurogenetic disorder characterized by multiple organ system involvement and a predisposition to benign and malignant tumor development. With revised NF1 clinical criteria...
19.
Furnari F, Anastasaki C, Bian S, Fine H, Koga T, Le L, et al.
Dis Model Mech
. 2024 Feb;
17(2).
PMID: 38353122
Nervous system tumors, particularly brain tumors, represent the most common tumors in children and one of the most lethal tumors in adults. Despite decades of research, there are few effective...
20.
Chatterjee J, Koleske J, Chao A, Sauerbeck A, Chen J, Qi X, et al.
Acta Neuropathol Commun
. 2024 Feb;
12(1):21.
PMID: 38308315
Tissue injury and tumorigenesis share many cellular and molecular features, including immune cell (T cells, monocytes) infiltration and inflammatory factor (cytokines, chemokines) elaboration. Their common pathobiology raises the intriguing possibility...