David Gresham
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Explore the profile of David Gresham including associated specialties, affiliations and a list of published articles.
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76
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2605
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Recent Articles
1.
Chuong J, Ben Nun N, Suresh I, Matthews J, De T, Avecilla G, et al.
Elife
. 2025 Feb;
13.
PMID: 39899365
Copy number variants (CNVs) are an important source of genetic variation underlying rapid adaptation and genome evolution. Whereas point mutation rates vary with genomic location and local DNA features, the...
2.
Spealman P, de Santana C, De T, Gresham D
Mol Biol Evol
. 2025 Jan;
42(2).
PMID: 39847535
Copy number variants (CNVs) are an important class of genetic variation that can mediate rapid adaptive evolution. Whereas, CNVs can increase the relative fitness of the organism, they can also...
3.
Chuong J, Ben Nun N, Suresh I, Matthews J, De T, Avecilla G, et al.
bioRxiv
. 2024 Oct;
PMID: 39464144
Copy number variants (CNVs)-gains and losses of genomic sequences-are an important source of genetic variation underlying rapid adaptation and genome evolution. However, despite their central role in evolution little is...
4.
Taneva A, Gresham D, Guergueltcheva V, Chamova T, Bojinova V, Gospodinova M, et al.
Genes (Basel)
. 2024 Sep;
15(9).
PMID: 39336735
Sarcoglycanopathies are among the most frequent and severe forms of autosomal recessive forms of limb-girdle muscular dystrophies (LGMDs) with childhood onset. Four subtypes are known: LGMDR3, LGMDR4, LGMDR5 and LGMDR6,...
5.
de Santana C, Spealman P, Oliveira E, Gresham D, de Jesus T, Chinalia F
PeerJ
. 2024 Aug;
12:e17900.
PMID: 39157765
The activities of microbiomes in river sediments play an important role in sustaining ecosystem functions by driving many biogeochemical cycles. However, river ecosystems are frequently affected by anthropogenic activities, which...
6.
Xie Y, Shu T, Liu T, Spindler M, Mahamid J, Hocky G, et al.
Mol Cell
. 2024 Jul;
84(14):2698-2716.e9.
PMID: 39059370
The cell interior is packed with macromolecules of mesoscale size, and this crowded milieu significantly influences cellular physiology. Cellular stress responses almost universally lead to inhibition of translation, resulting in...
7.
Mokhtari M, Amiri P, Miller D, Gresham D, Bloor S, Munkacsi A
G3 (Bethesda)
. 2024 May;
14(7).
PMID: 38805688
Nature has been a rich source of pharmaceutical compounds, producing 80% of our currently prescribed drugs. The feijoa plant, Acca sellowiana, is classified in the family Myrtaceae, native to South...
8.
Knoll M, Honce R, Meliopoulos V, Segredo-Otero E, Johnson K, Schultz-Cherry S, et al.
J Virol
. 2024 May;
98(6):e0177823.
PMID: 38785423
Obesity is well established as a risk factor for many noncommunicable diseases; however, its consequences for infectious disease are poorly understood. Here, we investigated the impact of host obesity on...
9.
Sevim Bayrak C, Forst C, Jones D, Gresham D, Pushalkar S, Wu S, et al.
bioRxiv
. 2024 Feb;
PMID: 38328256
Understanding the molecular mechanisms that underpin diverse vaccination responses is a critical step toward developing efficient vaccines. Molecular subtyping approaches can offer valuable insights into the heterogeneous nature of responses...
10.
Tjarnberg A, Beheler-Amass M, Jackson C, Christiaen L, Gresham D, Bonneau R
Genome Biol
. 2024 Jan;
25(1):24.
PMID: 38238840
Background: Modeling of gene regulatory networks (GRNs) is limited due to a lack of direct measurements of genome-wide transcription factor activity (TFA) making it difficult to separate covariance and regulatory...