David Gonzalez-Bullon
Overview
Explore the profile of David Gonzalez-Bullon including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
106
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0
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Recent Articles
1.
Etxaniz A, Gonzalez-Bullon D, Martin C, Alonso M, Ostolaza H
FEBS J
. 2019 Oct;
287(9):1798-1815.
PMID: 31652486
Rapid plasma membrane repair in response to pore-forming toxins is crucial for cell survival, but the molecular mechanisms employed by eukaryotic nucleated cells to maintain membrane integrity and the specificities...
2.
Ostolaza H, Gonzalez-Bullon D, Uribe K, Martin C, Amuategi J, Fernandez-Martinez X
Toxins (Basel)
. 2019 Jun;
11(6).
PMID: 31216745
Pore-forming toxins (PFTs) form nanoscale pores across target membranes causing cell death. The pore-forming cytolysins of the RTX (repeats in toxin) family belong to a steadily increasing family of proteins...
3.
Gonzalez-Bullon D, Uribe K, Largo E, Guembelzu G, Garcia-Arribas A, Martin C, et al.
Biomolecules
. 2019 May;
9(5).
PMID: 31083482
RTX (Repeats in ToXin) pore-forming toxins constitute an expanding family of exoproteins secreted by many -negative bacteria and involved in infectious diseases caused by said pathogens. Despite the relevance in...
4.
Gonzalez-Bullon D, Martin C, Ostolaza H
Toxins (Basel)
. 2018 Dec;
10(12).
PMID: 30518046
Adenylate cyclase toxin (ACT, CyaA) is one of the important virulence factors secreted by the whooping cough bacterium , and it is essential for the colonization of the human respiratory...
5.
Etxaniz A, Gonzalez-Bullon D, Martin C, Ostolaza H
Toxins (Basel)
. 2018 Jun;
10(6).
PMID: 29890730
Permeabilization of the plasma membrane represents an important threat for any cell, since it compromises its viability by disrupting cell homeostasis. Numerous pathogenic bacteria produce pore-forming toxins that break plasma...
6.
Ostolaza H, Martin C, Gonzalez-Bullon D, Uribe K, Etxaniz A
Toxins (Basel)
. 2017 Sep;
9(10).
PMID: 28934133
Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium , and it has a critical role in colonization of the respiratory...
7.
Gonzalez-Bullon D, Uribe K, Martin C, Ostolaza H
Proc Natl Acad Sci U S A
. 2017 Aug;
114(33):E6784-E6793.
PMID: 28760979
Adenylate cyclase toxin (ACT or CyaA) plays a crucial role in respiratory tract colonization and virulence of the whooping cough causative bacterium Secreted as soluble protein, it targets myeloid cells...
8.
Martin C, Etxaniz A, Uribe K, Etxebarria A, Gonzalez-Bullon D, Arlucea J, et al.
Sci Rep
. 2015 Sep;
5:13774.
PMID: 26346097
Bordetella pertussis causes whooping cough, a respiratory infectious disease that is the fifth largest cause of vaccine-preventable death in infants. Though historically considered an extracellular pathogen, this bacterium has been...
9.
Uribe K, Martin C, Etxebarria A, Gonzalez-Bullon D, Gomez-Bilbao G, Ostolaza H
PLoS One
. 2013 Sep;
8(9):e74248.
PMID: 24058533
Humans infected with Bordetella pertussis, the whooping cough bacterium, show evidences of impaired host defenses. This pathogenic bacterium produces a unique adenylate cyclase toxin (ACT) which enters human phagocytes and...