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David Garcia-Seisdedos

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Articles 17
Citations 3253
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Recent Articles
1.
Prakash A, Garcia-Seisdedos D, Wang S, Kundu D, Collins A, George N, et al.
J Proteome Res . 2022 Dec; 22(3):729-742. PMID: 36577097
The availability of proteomics datasets in the public domain, and in the PRIDE database, in particular, has increased dramatically in recent years. This unprecedented large-scale availability of data provides an...
2.
Molina Y, Garcia-Seisdedos D, Babiy B, Lerma M, Martinez-Botas J, Casarejos M, et al.
Biomedicines . 2022 Jun; 10(6). PMID: 35740338
Exosomes/microvesicles originate from multivesicular bodies that allow the secretion of endolysosome components out of the cell. In the present work, we investigated the effects of rottlerin, a polyphenol, on exosome/microvesicle...
3.
Wang S, Garcia-Seisdedos D, Prakash A, Kundu D, Collins A, George N, et al.
PLoS Comput Biol . 2022 Jun; 18(6):e1010174. PMID: 35714157
The increasingly large amount of proteomics data in the public domain enables, among other applications, the combined analyses of datasets to create comparative protein expression maps covering different organisms and...
4.
Walzer M, Garcia-Seisdedos D, Prakash A, Brack P, Crowther P, Graham R, et al.
Sci Data . 2022 Jun; 9(1):335. PMID: 35701420
The number of mass spectrometry (MS)-based proteomics datasets in the public domain keeps increasing, particularly those generated by Data Independent Acquisition (DIA) approaches such as SWATH-MS. Unlike Data Dependent Acquisition...
5.
Moreno P, Fexova S, George N, Manning J, Miao Z, Mohammed S, et al.
Nucleic Acids Res . 2021 Dec; 50(D1):D129-D140. PMID: 34850121
The EMBL-EBI Expression Atlas is an added value knowledge base that enables researchers to answer the question of where (tissue, organism part, developmental stage, cell type) and under which conditions...
6.
Perez-Riverol Y, Bai J, Bandla C, Garcia-Seisdedos D, Hewapathirana S, Kamatchinathan S, et al.
Nucleic Acids Res . 2021 Nov; 50(D1):D543-D552. PMID: 34723319
The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's largest data repository of mass spectrometry-based proteomics data. PRIDE is one of the founding members of the global ProteomeXchange (PX) consortium...
7.
Earl J, Barreto E, Castillo M, Fuentes R, Rodriguez-Garrote M, Ferreiro R, et al.
Cancers (Basel) . 2021 Aug; 13(15). PMID: 34359822
The authors wish to make the following corrections to this paper [...].
8.
Canfran-Duque A, Pastor O, Garcia-Seisdedos D, Molina Y, Babiy B, Lerma M, et al.
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33920193
Atypical or second-generation antipsychotics are used in the treatment of psychosis and behavioral problems in older persons with dementia. However, these pharmaceutical drugs are associated with an increased risk of...
9.
Earl J, Barreto E, Castillo M, Fuentes R, Rodriguez-Garrote M, Ferreiro R, et al.
Cancers (Basel) . 2021 Apr; 13(7). PMID: 33807330
Pancreatic ductal adenocarcinoma (PDAC) presents many challenges in the clinic and there are many areas for improvement in diagnostics and patient management. The five-year survival rate is around 7.2% as...
10.
Earl J, Galindo-Pumarino C, Encinas J, Barreto E, Castillo M, Pachon V, et al.
EBioMedicine . 2020 Mar; 53:102675. PMID: 32113160
Background: The 5-year survival rate of patients with pancreatic ductal adenocarcinoma (PDAC) is around 5% due to the fact that the majority of patients present with advanced disease that is...