David G Oscier
Overview
Explore the profile of David G Oscier including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
38
Citations
1507
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Parry M, Rose-Zerilli M, Gibson J, Ennis S, Walewska R, Forster J, et al.
PLoS One
. 2013 Dec;
8(12):e83244.
PMID: 24349473
The pathogenesis of splenic marginal zone lymphoma (SMZL) remains largely unknown. Recent high-throughput sequencing studies have identified recurrent mutations in key pathways, most notably NOTCH2 mutations in >25% of patients....
12.
Johnson G, Lin K, Cox T, Oates M, Sibson D, Eccles R, et al.
Blood
. 2013 Oct;
122(26):4253-8.
PMID: 24128861
Fludarabine plus cyclophosphamide (FC) is the chemotherapy backbone of modern chronic lymphocytic leukemia (CLL) treatment. CYP2B6 is a polymorphic cytochrome P450 isoform that converts cyclophosphamide to its active form. This...
13.
Oscier D, Rose-Zerilli M, Winkelmann N, Gonzalez de Castro D, Gomez B, Forster J, et al.
Blood
. 2012 Oct;
121(3):468-75.
PMID: 23086750
NOTCH1 and SF3B1 mutations have been previously reported to have prognostic significance in chronic lymphocytic leukemia but to date they have not been validated in a prospective, controlled clinical trial....
14.
Lin K, Adamson J, Johnson G, Carter A, Oates M, Wade R, et al.
Clin Cancer Res
. 2012 Jun;
18(15):4191-200.
PMID: 22675167
Purpose: This study sought to establish whether functional analysis of the ATM-p53-p21 pathway adds to the information provided by currently available prognostic factors in patients with chronic lymphocytic leukemia (CLL)...
15.
Skowronska A, Austen B, Powell J, Weston V, Oscier D, Dyer M, et al.
Haematologica
. 2011 Sep;
97(1):142-6.
PMID: 21933854
Ataxia telangiectasia patients, with constitutional bi-allelic ATM mutations, have a marked risk of lymphoid tumors and ATM mutation carriers have a smaller risk of cancer. Sporadic ATM mutations occur in...
16.
Lim S, Vaughan A, Ashton-Key M, Williams E, Dixon S, Chan H, et al.
Blood
. 2011 Jul;
118(9):2530-40.
PMID: 21768293
The anti-CD20 mAb rituximab is central to the treatment of B-cell malignancies, but resistance remains a significant problem. We recently reported that resistance could be explained, in part, by internalization...
17.
Wade R, Di Bernardo M, Richards S, Rossi D, Crowther-Swanepoel D, Gaidano G, et al.
Haematologica
. 2011 Jun;
96(10):1496-503.
PMID: 21659360
Background: There is variability in the outcome of patients with chronic lymphocytic leukemia with apparently the same stage of disease. Identifying genetic variants that influence patients' outcome and response to...
18.
Majid A, Lin T, Best G, Fishlock K, Hewamana S, Pratt G, et al.
Leuk Res
. 2010 Nov;
35(6):750-6.
PMID: 21093051
The world of chronic lymphocytic leukemia (CLL) research is awash with prognostic markers. However, very few of the current group play a clearly defined role in the pathology of this...
19.
Irving L, Mainou-Fowler T, Parker A, Ibbotson R, Oscier D, Strathdee G
Epigenetics
. 2010 Nov;
6(3):300-6.
PMID: 21051931
Chronic lymphocytic leukemia (CLL) exhibits a very variable clinical course. Altered DNA methylation of genes has shown promise as a source of novel prognostic makers in a number of cancers....
20.
Weston V, Oldreive C, Skowronska A, Oscier D, Pratt G, Dyer M, et al.
Blood
. 2010 Aug;
116(22):4578-87.
PMID: 20739657
The Ataxia Telangiectasia Mutated (ATM) gene is frequently inactivated in lymphoid malignancies such as chronic lymphocytic leukemia (CLL), T-prolymphocytic leukemia (T-PLL), and mantle cell lymphoma (MCL) and is associated with...