David G Allen
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Explore the profile of David G Allen including associated specialties, affiliations and a list of published articles.
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105
Citations
2753
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Recent Articles
1.
Reinke E, Reynolds J, Gilmour N, Reynolds G, Strickland J, Germolec D, et al.
Curr Res Toxicol
. 2025 Jan;
8():100205.
PMID: 39803375
Mechanistically based non-animal methods for assessing skin sensitization hazard have been developed, but are not considered sufficient, individually, to conclusively define the skin sensitization potential or potency of a chemical....
2.
Raabe H, Costin G, Allen D, Lowit A, Corvaro M, ODell L, et al.
Cutan Ocul Toxicol
. 2024 Aug;
:1-21.
PMID: 39180341
Test methods to inform hazard characterization and labeling of pesticides to protect human health are typically conducted using laboratory animals, and for skin irritation/corrosion the rabbit Draize test is currently...
3.
Kreutz A, Oyetade O, Chang X, Hsieh J, Behl M, Allen D, et al.
Toxics
. 2024 Jun;
12(6).
PMID: 38922117
Organophosphorus flame retardants (OPFRs) are abundant and persistent in the environment but have limited toxicity information. Their similarity in structure to organophosphate pesticides presents great concern for developmental neurotoxicity (DNT)....
4.
Stucki A, Sauer U, Allen D, Kleinstreuer N, Perron M, Yozzo K, et al.
Regul Toxicol Pharmacol
. 2024 May;
150:105648.
PMID: 38772524
Inhalation is a critical route through which substances can exert adverse effects in humans; therefore, it is important to characterize the potential effects that inhaled substances may have on the...
5.
Herzler M, Abedini J, Allen D, Germolec D, Gordon J, Ko H, et al.
Arch Toxicol
. 2024 Mar;
98(5):1253-1269.
PMID: 38483583
Since the 1940s, patch tests in healthy volunteers (Human Predictive Patch Tests, HPPTs) have been used to identify chemicals that cause skin sensitization in humans. Recently, we reported the results...
6.
van der Zalm A, Daniel A, Raabe H, Choksi N, Flint Silva T, Breeden-Alemi J, et al.
Cutan Ocul Toxicol
. 2023 Oct;
43(1):58-68.
PMID: 37905558
Many sectors have seen complete replacement of the rabbit eye test with reproducible and relevant and methods to assess the eye corrosion/irritation potential of chemicals. However, the rabbit eye test...
7.
Strickland J, Haugabrooks E, Allen D, Balottin L, Hirabayashi Y, Kleinstreuer N, et al.
Crit Rev Toxicol
. 2023 Aug;
53(7):385-411.
PMID: 37646804
Chemical regulatory authorities around the world require systemic toxicity data from acute exposures via the oral, dermal, and inhalation routes for human health risk assessment. To identify opportunities for regulatory...
8.
Strickland J, Abedini J, Allen D, Gordon J, Hull V, Kleinstreuer N, et al.
Arch Toxicol
. 2023 Aug;
97(11):2825-2837.
PMID: 37615678
Critical to the evaluation of non-animal tests are reference data with which to assess their relevance. Animal data are typically used because they are generally standardized and available. However, when...
9.
Sharma M, Stucki A, Verstraelen S, Stedeford T, Jacobs A, Maes F, et al.
Toxicol Sci
. 2023 Jul;
195(2):213-230.
PMID: 37498623
Inhalation is a major route by which human exposure to substances can occur. Resources have therefore been dedicated to optimize human-relevant in vitro approaches that can accurately and efficiently predict...
10.
Strickland J, Allen D, Germolec D, Kleinstreuer N, Johnson V, Gulledge T, et al.
Appl In Vitro Toxicol
. 2023 Jan;
8(4):117-128.
PMID: 36647556
Introduction: Isothiazolinones (ITs) are widely used as antimicrobial preservatives in cosmetics and as additives for preservation of consumer and industrial products to control bacteria, fungi, and algae. Although they are...