David E Condon
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Explore the profile of David E Condon including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
169
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Recent Articles
1.
Kwak S, Hernandez-Cancela R, DiCorpo D, Condon D, Merino J, Wu P, et al.
Diabetes Care
. 2024 Apr;
47(6):1042-1047.
PMID: 38652672
Objective: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). Research Design And Methods: We conducted a multiancestry time-to-event genome-wide association study...
2.
Kwak S, Hernandez-Cancela R, DiCorpo D, Condon D, Merino J, Wu P, et al.
medRxiv
. 2023 Aug;
PMID: 37546893
Background: Type 2 diabetes mellitus (T2D) confers a two- to three-fold increased risk of cardiovascular disease (CVD). However, the mechanisms underlying increased CVD risk among people with T2D are only...
3.
Cherukuri P, Soe M, Condon D, Bartaria S, Meis K, Gu S, et al.
BMC Med Genomics
. 2022 Mar;
15(1):56.
PMID: 35287663
Background: Clinical use of genotype data requires high positive predictive value (PPV) and thorough understanding of the genotyping platform characteristics. BeadChip arrays, such as the Global Screening Array (GSA), potentially...
4.
Pinney S, Joshi A, Yin V, Min S, Rashid C, Condon D, et al.
J Clin Endocrinol Metab
. 2020 Jul;
105(10).
PMID: 32687192
Context: Gestational diabetes (GDM) has profound effects on the intrauterine metabolic milieu and is linked to obesity and diabetes in offspring, but the mechanisms driving these effects remain largely unknown....
5.
Bansal A, Robles-Matos N, Wang P, Condon D, Joshi A, Pinney S
J Clin Endocrinol Metab
. 2019 Sep;
105(2).
PMID: 31536135
Context: Prenatal exposure to bisphenol A (BPA) is linked to obesity and diabetes but the molecular mechanisms driving these phenomena are not known. Alterations in deoxyribonucleic acid (DNA) methylation in...
6.
Lien Y, Condon D, Georgieff M, Simmons R, Tran P
Nutrients
. 2019 May;
11(5).
PMID: 31137889
Early-life iron deficiency results in long-term abnormalities in cognitive function and affective behavior in adulthood. In preclinical models, these effects have been associated with long-term dysregulation of key neuronal genes....
7.
Condon D, Tran P, Lien Y, Schug J, Georgieff M, Simmons R, et al.
BMC Bioinformatics
. 2018 Feb;
19(1):31.
PMID: 29402210
Background: Identification of differentially methylated regions (DMRs) is the initial step towards the study of DNA methylation-mediated gene regulation. Previous approaches to call DMRs suffer from false prediction, use extreme...
8.
Pinamonti G, Zhao J, Condon D, Paul F, Noe F, Turner D, et al.
J Chem Theory Comput
. 2016 Dec;
13(2):926-934.
PMID: 28001394
Nowadays different experimental techniques, such as single molecule or relaxation experiments, can provide dynamic properties of biomolecular systems, but the amount of detail obtainable with these methods is often limited...
9.
Condon D, Kennedy S, Mort B, Kierzek R, Yildirim I, Turner D
J Chem Theory Comput
. 2015 Jun;
11(6):2729-2742.
PMID: 26082675
Molecular dynamics (MD) simulations for RNA tetramers r(AAAA), r(CAAU), r(GACC), and r(UUUU) are benchmarked against H-H NOESY distances and scalar couplings to test effects of RNA torsion parametrizations. Four different...
10.
Condon D, Yildirim I, Kennedy S, Mort B, Kierzek R, Turner D
J Phys Chem B
. 2014 Jan;
118(5):1216-28.
PMID: 24377321
Locked Nucleic Acids (LNAs) are RNA analogues with an O2'-C4' methylene bridge which locks the sugar into a C3'-endo conformation. This enhances hybridization to DNA and RNA, making LNAs useful...