David Darling
Overview
Explore the profile of David Darling including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
25
Citations
431
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0
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Recent Articles
21.
Nesbeth D, Williams S, Chan L, Brain T, Slater N, Farzaneh F, et al.
Mol Ther
. 2005 Nov;
13(4):814-22.
PMID: 16298167
Nonviral, host-derived proteins on lentiviral vector surfaces can have a profound effect on the vector's biology as they can both promote infection and provide resistance to complement inactivation. We have...
22.
Chan L, Nesbeth D, Mackey T, Galea-Lauri J, Gaken J, Martin F, et al.
J Virol
. 2005 Sep;
79(20):13190-4.
PMID: 16189021
Nonviral producer cell proteins incorporated into retroviral vector surfaces profoundly influence infectivity and in vivo half-life. We report the purification and concentration of lentiviral vectors using these surface proteins as...
23.
Chandrashekran A, Gordon M, Darling D, Farzaneh F, Casimir C
J Gene Med
. 2004 Oct;
6(11):1189-96.
PMID: 15468194
Background: The therapeutic potential of retroviruses can be significantly enhanced by display of specific molecules on the retroviral surface. This has been conventionally achieved by the manipulation of retroviral envelope...
24.
Galea-Lauri J, Wells J, Darling D, Harrison P, Farzaneh F
Cancer Immunol Immunother
. 2004 May;
53(11):963-77.
PMID: 15146294
Dendritic cells (DCs) primed with tumor antigens (Ags) can stimulate tumor rejection. This study was aimed at evaluating the polarization of T-cell responses using various DC Ag-priming strategies for vaccination...
25.
Galea-Lauri J, Darling D, Mufti G, Harrison P, Farzaneh F
Cancer Immunol Immunother
. 2002 Jul;
51(6):299-310.
PMID: 12111118
Dendritic cells (DC) have been successfully used in clinical pilot studies to induce tumor-specific immunity as well as clinical response in selected patients. However, DC-based immunotherapy remains a challenge and...