David Canner
Overview
Explore the profile of David Canner including associated specialties, affiliations and a list of published articles.
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10
Citations
882
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0
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Recent Articles
1.
Burger M, Cruz A, Crossland G, Gaglia G, Ritch C, Blatt S, et al.
Cell
. 2021 Sep;
184(19):4996-5014.e26.
PMID: 34534464
CD8 T cell responses against different tumor neoantigens occur simultaneously, yet little is known about the interplay between responses and its impact on T cell function and tumor control. In...
2.
Schenkel J, Herbst R, Canner D, Li A, Hillman M, Shanahan S, et al.
Immunity
. 2021 Sep;
54(10):2338-2353.e6.
PMID: 34534439
In tumors, a subset of CD8 T cells expressing the transcription factor TCF-1 drives the response to immune checkpoint blockade. We examined the mechanisms that maintain these cells in an...
3.
Marjanovic N, Hofree M, Chan J, Canner D, Wu K, Trakala M, et al.
Cancer Cell
. 2020 Jul;
38(2):229-246.e13.
PMID: 32707077
Tumor evolution from a single cell into a malignant, heterogeneous tissue remains poorly understood. Here, we profile single-cell transcriptomes of genetically engineered mouse lung tumors at seven stages, from pre-neoplastic...
4.
Li A, Herbst R, Canner D, Schenkel J, Smith O, Kim J, et al.
Cell Rep
. 2019 Dec;
29(10):2998-3008.e8.
PMID: 31801068
Regulatory T cells (T) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. T in human tumors span diverse transcriptional states distinct from those...
5.
Lee J, Tammela T, Hofree M, Choi J, Marjanovic N, Han S, et al.
Cell
. 2017 Sep;
170(6):1149-1163.e12.
PMID: 28886383
The diversity of mesenchymal cell types in the lung that influence epithelial homeostasis and regeneration is poorly defined. We used genetic lineage tracing, single-cell RNA sequencing, and organoid culture approaches...
6.
Zawislak C, Beaulieu A, Loeb G, Karo J, Canner D, Bezman N, et al.
Proc Natl Acad Sci U S A
. 2013 Apr;
110(17):6967-72.
PMID: 23572582
Natural killer (NK) cells function in the recognition and destruction of host cells infected with pathogens. Many regulatory mechanisms govern the potent responses of NK cells, both at the cellular...
7.
Loeb G, Khan A, Canner D, Hiatt J, Shendure J, Darnell R, et al.
Mol Cell
. 2012 Nov;
48(5):760-70.
PMID: 23142080
MicroRNAs (miRNAs) are essential components of gene regulation, but identification of miRNA targets remains a major challenge. Most target prediction and discovery relies on perfect complementarity of the miRNA seed...
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9.
Prilusky J, Hodis E, Canner D, Decatur W, Oberholser K, Martz E, et al.
J Struct Biol
. 2011 May;
175(2):244-52.
PMID: 21536137
Proteopedia is a collaborative, 3D web-encyclopedia of protein, nucleic acid and other biomolecule structures. Created as a means for communicating biomolecule structures to a diverse scientific audience, Proteopedia (http://www.proteopedia.org) presents...
10.