David Beidler
Overview
Explore the profile of David Beidler including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
497
Followers
0
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Related Specialties
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Recent Articles
11.
Wang J, Bowen S, Schweitzer B, Madsen H, McDonald J, Pelc M, et al.
Bioorg Med Chem Lett
. 2009 Sep;
19(20):5970-4.
PMID: 19765986
Fatty acid amide hydrolase (FAAH) has attracted significant attention due to its promise as an analgesic target. This has resulted in the discovery of numerous chemical classes as inhibitors of...
12.
Ahn K, Johnson D, Mileni M, Beidler D, Long J, McKinney M, et al.
Chem Biol
. 2009 Apr;
16(4):411-20.
PMID: 19389627
Endocannabinoids are lipid signaling molecules that regulate a wide range of mammalian behaviors, including pain, inflammation, and cognitive/emotional state. The endocannabinoid anandamide is principally degraded by the integral membrane enzyme...
13.
Johnson D, Ahn K, Kesten S, Lazerwith S, Song Y, Morris M, et al.
Bioorg Med Chem Lett
. 2009 Apr;
19(10):2865-9.
PMID: 19386497
The synthesis and structure-activity relationships (SAR) of a series of benzothiophene piperazine and piperidine urea FAAH inhibitors is described. These compounds inhibit FAAH by covalently modifying the enzyme's active site...