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David Abood

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Articles 5
Citations 194
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Recent Articles
1.
Angell C, Sun S, Lapurga G, Benner B, Quiroga D, Savardekar H, et al.
Melanoma Res . 2025 Jan; 35(2):102-108. PMID: 39883562
Myeloid-derived suppressor cells (MDSCs) are expanded in cancer patients, have an intrinsic immunosuppressive function, and thus may play a role in resistance to immunotherapy. Ulceration of the melanoma primary is...
2.
Sun S, Angell C, Savardekar H, Sundi D, Abood D, Benner B, et al.
Cancer Immunol Immunother . 2023 Aug; 72(11):3461-3474. PMID: 37528320
Myeloid-derived suppressor cells (MDSC) have been linked to loss of immune effector cell function through a variety of mechanisms such as the generation of reactive oxygen and nitrogen species and...
3.
Sun S, Benner B, Savardekar H, Lapurga G, Good L, Abood D, et al.
Front Immunol . 2021 Oct; 12:740890. PMID: 34712230
Introduction: Myeloid-derived suppressor cells (MDSC) are a subset of immature myeloid cells that inhibit anti-tumor immunity and contribute to immune therapy resistance. MDSC populations were measured in melanoma patients receiving...
4.
Pinette A, McMichael E, Courtney N, Duggan M, Benner B, Choueiry F, et al.
Cancer Immunol Immunother . 2019 Jul; 68(8):1379-1389. PMID: 31338557
Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide and epidermal growth factor receptor (EGFR) is overexpressed in greater than 90% of patient...
5.
Stiff A, Trikha P, Mundy-Bosse B, McMichael E, Mace T, Benner B, et al.
Clin Cancer Res . 2018 Jan; 24(8):1891-1904. PMID: 29363526
mAbs are used to treat solid and hematologic malignancies and work in part through Fc receptors (FcRs) on natural killer cells (NK). However, FcR-mediated functions of NK cells from patients...
6.
Trikha P, Plews R, Stiff A, Gautam S, Hsu V, Abood D, et al.
Oncoimmunology . 2016 Oct; 5(9):e1214787. PMID: 27757311
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of early myeloid cells that accumulate in the blood and tumors of patients with cancer. MDSC play a critical role during tumor...