David A Carlson
Overview
Explore the profile of David A Carlson including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
510
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0
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Recent Articles
1.
Al-Ghabkari A, Carlson D, Haystead T, MacDonald J
bioRxiv
. 2024 Mar;
PMID: 38496458
Zipper-interacting protein kinase (ZIPK) is a Ser/Thr protein kinase with regulatory involvement in vascular smooth muscle cell (VSMC) actin polymerization and focal adhesion assembly dynamics. ZIPK silencing can induce cytoskeletal...
2.
Turner S, Al-Ghabkari A, Carlson D, Chappellaz M, Sutherland C, Haystead T, et al.
Exp Physiol
. 2023 Apr;
108(7):986-997.
PMID: 37084168
New Findings: What is the central question of this study? DAPK3 contributes to the Ca -sensitization of vascular smooth muscle contraction: does this protein kinase participate in the myogenic response...
3.
Scarneo S, Hughes P, Yang K, Carlson D, Gurbani D, Westover K, et al.
J Biol Chem
. 2020 Jan;
295(6):1565-1574.
PMID: 31914413
Interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-4, as well as transforming growth factor β-activated kinase 1 (TAK1), are protein kinases essential for transducing inflammatory signals from interleukin receptors. IRAK family proteins...
4.
Liao K, Sandall C, Carlson D, Ulke-Lemee A, Platnich J, Hughes P, et al.
Arch Biochem Biophys
. 2019 Jan;
670:104-115.
PMID: 30641048
The NLRP proteins are a subfamily of the NOD-like receptor (NLR) innate immune sensors that possess an ATP-binding NACHT domain. As the most well studied member, NLRP3 can initiate the...
5.
Carlson D, Singer M, Sutherland C, Redondo C, Alexander L, Hughes P, et al.
Cell Chem Biol
. 2018 Jul;
25(10):1195-1207.e32.
PMID: 30033129
Sustained vascular smooth muscle hypercontractility promotes hypertension and cardiovascular disease. The etiology of hypercontractility is not completely understood. New therapeutic targets remain vitally important for drug discovery. Here we report...
6.
Bellaye P, Shimbori C, Yanagihara T, Carlson D, Hughes P, Upagupta C, et al.
Eur Respir J
. 2018 Feb;
51(2).
PMID: 29386344
Idiopathic pulmonary fibrosis (IPF) is a progressive disease of the lung parenchyma, causing significant morbidity through worsening dyspnoea and overall functional decline. IPF is characterised by apoptosis-resistant myofibroblasts, which are...
7.
Zhu C, Martinez A, Martin H, Li M, Crouch B, Carlson D, et al.
Sci Rep
. 2017 Oct;
7(1):13772.
PMID: 29062013
While the demand for metabolic imaging has increased in recent years, simultaneous in vivo measurement of multiple metabolic endpoints remains challenging. Here we report on a novel technique that provides...
8.
Totzke J, Gurbani D, Raphemot R, Hughes P, Bodoor K, Carlson D, et al.
Cell Chem Biol
. 2017 Aug;
24(8):1029-1039.e7.
PMID: 28820959
Tumor necrosis factor alpha (TNF-α) has both positive and negative roles in human disease. In certain cancers, TNF-α is infused locally to promote tumor regression, but dose-limiting inflammatory effects limit...
9.
Alwarawrah Y, Hughes P, Loiselle D, Carlson D, Darr D, Jordan J, et al.
Cell Chem Biol
. 2016 Jun;
23(6):678-88.
PMID: 27265747
Many tumors are dependent on de novo fatty acid synthesis to maintain cell growth. Fatty acid synthase (FASN) catalyzes the final synthetic step of this pathway, and its upregulation is...
10.
MacDonald J, Sutherland C, Carlson D, Bhaidani S, Al-Ghabkari A, Sward K, et al.
Mol Pharmacol
. 2015 Oct;
89(1):105-17.
PMID: 26464323
A novel inhibitor of zipper-interacting protein kinase (ZIPK) was used to examine the involvement of ZIPK in the regulation of smooth muscle contraction. Pretreatment of de-endothelialized rat caudal arterial smooth...