David A Armstrong
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Explore the profile of David A Armstrong including associated specialties, affiliations and a list of published articles.
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57
Citations
1543
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Recent Articles
1.
Muse M, Wang Y, Gilbert-Diamond D, Armstrong D, Hoen A, Romano M, et al.
Eur J Nutr
. 2025 Feb;
64(2):75.
PMID: 39891736
Purpose: During pregnancy, extracellular vesicle and particle microRNAs (EVP miRNA) in maternal circulation have the capacity to cross the placenta and facilitate maternal-fetal communication. Both dysregulation of circulating EVP miRNA...
2.
Muse M, Armstrong D, Hoen A, Gilbert-Diamond D, Gui J, Palys T, et al.
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38338815
MicroRNAs (miRNA) in extracellular vesicles and particles (EVPs) in maternal circulation during pregnancy and in human milk postpartum are hypothesized to facilitate maternal-offspring communication via epigenetic regulation. However, factors influencing...
3.
Howe C, Armstrong D, Muse M, Gilbert-Diamond D, Gui J, Hoen A, et al.
Expo Health
. 2023 Dec;
15(4):731-743.
PMID: 38074282
Human milk is a rich source of microRNAs (miRNAs), which can be transported by extracellular vesicles and particles (EVPs) and are hypothesized to contribute to maternal-offspring communication and child development....
4.
Armstrong D, Hudson T, Hodge C, Hampton T, Howell A, Hayden M
RNA Biol
. 2023 Jun;
20(1):296-305.
PMID: 37287312
Gene editing using CRISPR/Cas (clustered regularly interspaced palindromic repeats/CRISPR-associated) is under development as a therapeutic tool for the modification of genes in eukaryotic cells. While much effort has focused on...
5.
Armstrong D, Hudson T, Hodge C, Hampton T, Howell A, Hayden M
bioRxiv
. 2023 Jan;
PMID: 36711562
CRISPR/Cas is under development as a therapeutic tool for the cleavage, excision, and/or modification of genes in eukaryotic cells. While much effort has focused on CRISPR/Cas from (SpCas9) and (SaCas9),...
6.
Prasad A, Tiwari C, Ray S, Holden S, Armstrong D, Rosengren K, et al.
Chempluschem
. 2022 Jan;
87(1):e202100408.
PMID: 35032115
Secondary structure changes are an inherent part of antimicrobial (AMP) and amyloidogenic peptide activity, especially in close proximity to membranes, and impact the peptides' function and dysfunction roles. The formation,...
7.
Armstrong D, Jin A, Braga Emidio N, Lewis R, Alewood P, Rosengren K
Mar Drugs
. 2021 Feb;
19(2).
PMID: 33530397
Conotoxins are disulfide-rich peptides found in the venom of cone snails. Due to their exquisite potency and high selectivity for a wide range of voltage and ligand gated ion channels...
8.
Lee M, Armstrong D, Hazlett H, Dessaint J, Mellinger D, Aridgides D, et al.
Epigenetics
. 2020 Dec;
16(11):1187-1200.
PMID: 33380271
Various pathogens use differing strategies to evade host immune response including modulating the host's epigenome. Here, we investigate if EVs secreted from alter DNA methylation in human lung macrophages, thereby...
9.
Armstrong D, Lee M, Hazlett H, Dessaint J, Mellinger D, Aridgides D, et al.
Immunohorizons
. 2020 Aug;
4(8):508-519.
PMID: 32819967
, a Gram-negative bacterium, is one of the most common pathogens colonizing the lungs of cystic fibrosis patients. secrete extracellular vesicles (EVs) that contain LPS and other virulence factors that...
10.
Identification of Let-7f-5p as a novel biomarker of recurrence in non-muscle invasive bladder cancer
Shee K, Seigne J, Karagas M, Marsit C, Hinds J, Schned A, et al.
Cancer Biomark
. 2020 Jul;
29(1):101-110.
PMID: 32623385
Background: Among patients diagnosed with non-muscle invasive bladder cancer (NMIBC), 30% to 70% experience recurrences within 6 to 12 years of diagnosis. The need to screen for these events every...