Dattatray Modhave
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Explore the profile of Dattatray Modhave including associated specialties, affiliations and a list of published articles.
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13
Citations
40
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Recent Articles
1.
Modhave D, Vrielynck S, Roeleveld K
Pharmaceutics
. 2024 Nov;
16(11).
PMID: 39598524
To evaluate and project the shelf life of GLPG4399, an early-phase clinical drug formulation by applying the Accelerated Stability Assessment Program (ASAP) approach. Forced degradation conditions were implemented to identify...
2.
Modhave D, Barrios B, Iyer J, Paudel A
AAPS PharmSciTech
. 2023 Dec;
25(1):10.
PMID: 38158448
The present study investigates the impact of the solid-state disorder of vortioxetine hydrobromide (HBr) on oxidative degradation under accelerated conditions. A range of solid-state disorders was generated via cryogenic ball...
3.
Iyer J, Brunsteiner M, Modhave D, Paudel A
J Pharm Sci
. 2023 Feb;
112(6):1539-1565.
PMID: 36842482
Common energy-intensive processes applied in oral solid dosage development, such as milling, sieving, blending, compaction, etc. generate particles with surface and bulk crystal disorder. An intriguing aspect of the generated...
4.
Saraf I, Kushwah V, Alva C, Koutsamanis I, Rattenberger J, Schroettner H, et al.
Mol Pharm
. 2023 Jan;
20(2):1307-1322.
PMID: 36680524
The present study deals with the development of dexamethasone (DM)-loaded implants using ester end-capped Resomer RG 502 poly(lactic acid-co-glycolic acid) (PLGA) (502), acid end-capped Resomer RG 502H PLGA (502H), and...
5.
Saraf I, Roskar R, Modhave D, Brunsteiner M, Karn A, Neshchadin D, et al.
Mol Pharm
. 2022 Jan;
19(2):568-583.
PMID: 35060741
In the present study, the oxidative degradation behavior of nifedipine (NIF) in amorphous solid dispersions (ASDs) prepared with poly(vinyl pyrrolidone) (PVP) with a short (K30) and a long (K90) chain...
6.
Ladumor M, Paudel A, Modhave D, Sharma S, Balhara A, Singh D, et al.
J Pharm Sci
. 2021 Oct;
111(5):1224-1231.
PMID: 34699842
This commentary presents contributions and accomplishments of Professor Saranjit Singh, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, India, to pharmaceutical research and education. Prof. Singh completed his...
7.
Kushwah V, Arora S, Katona M, Modhave D, Frohlich E, Paudel A
Pharmaceutics
. 2021 Mar;
13(2).
PMID: 33672439
The present work evaluates the food effect on the absorption of rivaroxaban (Riva), a BCS II drug, from the orally administered commercial immediate-release tablet (Xarelto IR) using physiologically based pharmacokinetic...
8.
Kushwah V, Saraf I, Yeoh T, Ardelean I, Weber H, Sarkar A, et al.
Mol Pharm
. 2021 Jan;
18(3):862-877.
PMID: 33475378
The present study investigates the chemical composition governing the physical properties of mono- and diglycerides (MDGs) at the microstructural level, as a function of aging and lot-to-lot variability. The physical...
9.
Saraf I, Kushwah V, Weber H, Modhave D, Yeoh T, Paudel A
AAPS PharmSciTech
. 2020 Dec;
22(1):11.
PMID: 33270172
Glycerides are the main components of oils, and fats, used in formulated products in the food and cosmetic industry as well as in the pharmaceutical product industry. However, there is...
10.
Modhave D, Saraf I, Karn A, Paudel A
AAPS PharmSciTech
. 2020 May;
21(5):152.
PMID: 32440782
The present study investigates concomitant processes of solid-state disordering and oxidation of simvastatin during milling. The separate dry ball milling of crystalline and amorphous powders of simvastatin were conducted at...