Peter Laggner
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Explore the profile of Peter Laggner including associated specialties, affiliations and a list of published articles.
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48
Citations
451
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Recent Articles
1.
Salar-Behzadi S, Corzo C, Laggner P
J Vis Exp
. 2022 Aug;
(186).
PMID: 36036623
Lipid-based excipients (LBEs) are low-toxic, biocompatible, and natural-based, and their application supports the sustainability of pharmaceutical manufacturing. However, the major challenge is their unstable solid-state, affecting the stability of the...
2.
Beretta M, Pinto J, Laggner P, Paudel A
Mol Pharm
. 2022 Jan;
19(2):547-557.
PMID: 35044180
The impact of the crystallinity of organic solid materials on their tribocharging propensity is well reported. However, no unequivocal explanation about the potential underlying mechanism(s) could be found so far...
3.
Kushwah V, Gomes Lopes D, Saraf I, Koutsamanis I, Werner B, Zangger K, et al.
Mol Pharm
. 2021 Dec;
19(2):532-546.
PMID: 34958588
The present study systematically investigates the effect of annealing conditions and the Kolliphor P 407 content on the physicochemical and structural properties of Compritol (glyceryl behenate) and ternary systems prepared...
4.
Schertel S, Salar-Behzadi S, Karrer J, Laggner P, Zimmer A
Int J Pharm
. 2021 Aug;
607:120970.
PMID: 34363917
Hydrochlorothiazide (HCT) multiparticulate systems (MPS) were hot melt coated with the binary mixture of tripalmitin (PPP) and polysorbate 65 (PS 65) to gain an immediate release profile. Once, HCT MPS...
5.
Radivojev S, Luschin-Ebengreuth G, Pinto J, Laggner P, Cavecchi A, Cesari N, et al.
Int J Pharm
. 2021 Jul;
606:120893.
PMID: 34274456
Orally inhaled products (OIPs) are gaining increased attention, as pulmonary delivery is a preferred route for the treatment of various diseases. Yet, the field of inhalation biopharmaceutics is still in...
6.
Kushwah V, Saraf I, Yeoh T, Ardelean I, Weber H, Sarkar A, et al.
Mol Pharm
. 2021 Jan;
18(3):862-877.
PMID: 33475378
The present study investigates the chemical composition governing the physical properties of mono- and diglycerides (MDGs) at the microstructural level, as a function of aging and lot-to-lot variability. The physical...
7.
Draksler P, Mikac U, Laggner P, Paudel A, Jankovic B
Acta Pharm
. 2020 Nov;
71(2):215-243.
PMID: 33151172
This article describes the designing of matrix tablets composed of polyethylene oxides (PEOs) with relative molecular masses of 1 × 106, 2 × 106, and 4 × 106. Percolation thresholds...
8.
Mirtic J, Paudel A, Laggner P, Hudoklin S, Kreft M, Kristl J
Int J Pharm
. 2020 Mar;
580:119199.
PMID: 32147494
Previously, we reported on the surfactant cetylpyridinium chloride (CPC) as a crosslinker of alginate for the formation of stable polyelectrolyte-surfactant-complex nanoparticles. Here, we evaluate this system for increased solubility of...
9.
Kushwah V, Gomes Lopes D, Koutsamanis I, Plank H, Ardelean I, Sarkar A, et al.
Eur J Pharm Sci
. 2020 Mar;
147:105278.
PMID: 32135269
The present study investigates the drug release-governing microstructural properties of melt spray congealed microspheres encapsulating the drug crystals in the matrix of glyceryl behenate and poloxamer (pore former). The solid-state,...
10.
Modhave D, Laggner P, Brunsteiner M, Paudel A
J Pharm Sci
. 2019 Jun;
108(10):3272-3280.
PMID: 31173762
The present study investigated the impact of solid-state disorders generated during milling on the chemical reactivity of simvastatin. An amorphous and a partially crystalline simvastatin powders were generated via cryomilling...