Darren Wethington
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Explore the profile of Darren Wethington including associated specialties, affiliations and a list of published articles.
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5
Citations
84
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Recent Articles
1.
Wethington D, Ahmad S, Potempa M, Giuliani G, Aguilar O, Poudel M, et al.
bioRxiv
. 2025 Mar;
PMID: 40060511
Natural killer (NK) cells are classically defined as innate immune cells, but experiments show that mouse cytomegalovirus (MCMV) infection in C57BL/6 mice can cause NK cells to undergo antigen-specific proliferation...
2.
Wethington D, Mukherjee S, Das J
Quant Biol
. 2023 May;
11(1):59-71.
PMID: 37123637
Background: Mass cytometry (CyTOF) gives unprecedented opportunity to simultaneously measure up to 40 proteins in single cells, with a theoretical potential to reach 100 proteins. This high-dimensional single-cell information can...
3.
Mukherjee S, Wethington D, Dey T, Das J
PLoS Comput Biol
. 2022 Mar;
18(3):e1009931.
PMID: 35312683
Cytometry experiments yield high-dimensional point cloud data that is difficult to interpret manually. Boolean gating techniques coupled with comparisons of relative abundances of cellular subsets is the current standard for...
4.
Mukherjee S, Wethington D, Dey T, Das J
bioRxiv
. 2021 May;
PMID: 33948593
Author Summary: Identifying differences between cytometry data seen as a point cloud can be complicated by random variations in data collection and data sources. We apply used in to describe...
5.
Kararoudi M, Nagai Y, Elmas E, de Souza Fernandes Pereira M, Ali S, Imus P, et al.
Blood
. 2020 Jul;
136(21):2416-2427.
PMID: 32603414
Multiple myeloma (MM) is a plasma cell neoplasm that commonly expresses CD38. Daratumumab (DARA), a human monoclonal antibody targeting CD38, has significantly improved the outcome of patients with relapsed or...
6.
Wethington D, Harder O, Uppulury K, Stewart W, Chen P, King T, et al.
J R Soc Interface
. 2019 Nov;
16(160):20190389.
PMID: 31771450
Respiratory syncytial virus (RSV) is a common virus that can have varying effects ranging from mild cold-like symptoms to mortality depending on the age and immune status of the individual....