Darren D Thomson
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Explore the profile of Darren D Thomson including associated specialties, affiliations and a list of published articles.
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15
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100
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Recent Articles
1.
Giner-Llorca M, Ropero-Perez C, Garrigues S, Thomson D, Bignell E, Manzanares P, et al.
Int J Biol Macromol
. 2024 Oct;
282(Pt 5):136980.
PMID: 39471922
Antifungal proteins (AFPs) as the highly active PeAfpA from Penicillium expansum or PdAfpB from Penicillium digitatum exert promising antifungal activity, but their mode of action is not fully understood. We...
2.
Bertuzzi M, Howell G, Thomson D, Fortune-Grant R, Moslinger A, Dancer P, et al.
iScience
. 2024 Jun;
27(6):109939.
PMID: 38846001
Hundreds of spores of are inhaled daily by human beings, representing a constant, possibly fatal, threat to respiratory health. The small size of spores suggests that interactions with alveolar epithelial...
3.
Francis V, Liddle C, Camacho E, Kulkarni M, Junior S, Harvey J, et al.
mBio
. 2024 Mar;
15(4):e0307823.
PMID: 38511961
causes lethal meningitis and accounts for approximately 10%-15% of AIDS-associated deaths worldwide. There are major gaps in our understanding of how this fungus invades the mammalian brain. To investigate the...
4.
Francis V, Liddle C, Camacho E, Kulkarni M, Junior S, Harvey J, et al.
bioRxiv
. 2023 Nov;
PMID: 38014111
The fungus causes lethal meningitis in humans with weakened immune systems and is estimated to account for 10-15% of AIDS-associated deaths worldwide. There are major gaps in our understanding of...
5.
John L, Thomson D, Bicanic T, Hoenigl M, Brown A, Harrison T, et al.
Antimicrob Agents Chemother
. 2023 May;
67(6):e0164522.
PMID: 37162367
Candida auris is an emerging, multidrug-resistant fungal pathogen that causes refractory colonization and life-threatening, invasive nosocomial infections. The high proportion of C. auris isolates that display antifungal resistance severely limits...
6.
Okaa U, Bertuzzi M, Fortune-Grant R, Thomson D, Moyes D, Naglik J, et al.
Infect Immun
. 2023 Jan;
91(2):e0033322.
PMID: 36625602
The human lung is constantly exposed to Aspergillus fumigatus spores, the most prevalent worldwide cause of fungal respiratory disease. Pulmonary tissue damage is a unifying feature of Aspergillus-related diseases; however,...
7.
Rahman S, van Rhijn N, Papastamoulis P, Thomson D, Carter Z, Fortune-Grant R, et al.
Front Cell Infect Microbiol
. 2022 Aug;
12:907519.
PMID: 35982778
Damage to the lung epithelium is a unifying feature of disease caused by the saprophytic fungus . However, the mechanistic basis and the regulatory control of such damage is poorly...
8.
Garcia-Rodriguez K, Goenka A, Thomson D, Bahri R, Tontini C, Salcman B, et al.
Int J Mol Sci
. 2022 Jul;
23(14).
PMID: 35886897
Bacillus Calmette-Guérin (BCG) vaccine is an attenuated strain of that provides weak protection against tuberculosis (TB). Mast cells (MCs) are tissue-resident immune cells strategically that serve as the first line...
9.
Ortiz S, Pennington K, Thomson D, Bertuzzi M
J Fungi (Basel)
. 2022 Mar;
8(3).
PMID: 35330266
spores initiate more than 3,000,000 chronic and 300,000 invasive diseases annually, worldwide. Depending on the immune status of the host, inhalation of these spores can lead to a broad spectrum...
10.
Brun S, Kuo H, Jeffree C, Thomson D, Read N
Microbiol Spectr
. 2021 Oct;
9(2):e0033521.
PMID: 34612669
Sexual reproduction is a key process influencing the evolution and adaptation of animals, plants, and many eukaryotic microorganisms, such as fungi. However, the sequential cell biology of fertilization and the...