Darrell R Boverhof
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Explore the profile of Darrell R Boverhof including associated specialties, affiliations and a list of published articles.
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31
Citations
548
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Recent Articles
1.
LeBaron M, Hotchkiss J, Zhang F, Koehler M, Boverhof D
J Appl Toxicol
. 2020 Aug;
41(3):362-374.
PMID: 32830330
1,2-dichloroethane (DCE or EDC) is a chlorinated hydrocarbon used as a chemical intermediate, including in the synthesis of polyvinyl chloride. Although DCE has induced tumors in both rats and mice,...
2.
Settivari R, Amado R, Corvaro M, Visconti N, Kan L, Carney E, et al.
Regul Toxicol Pharmacol
. 2016 Oct;
81:407-420.
PMID: 27693708
Agrochemical formulations have been underrepresented in validation efforts for implementing alternative eye irritation approaches but represent a significant opportunity to reduce animal testing. This study assesses the utility of the...
3.
Boverhof D, Bramante C, Butala J, Clancy S, Lafranconi M, West J, et al.
Regul Toxicol Pharmacol
. 2015 Jun;
73(1):137-50.
PMID: 26111608
Nanomaterials continue to bring promising advances to science and technology. In concert have come calls for increased regulatory oversight to ensure their appropriate identification and evaluation, which has led to...
4.
Settivari R, Gehen S, Amado R, Visconti N, Boverhof D, Carney E
Regul Toxicol Pharmacol
. 2015 May;
72(2):350-60.
PMID: 25981449
Assessment of skin sensitization potential is an important component of the safety evaluation process for agrochemical products. Recently, non-animal approaches including the KeratinoSens™ assay have been developed for predicting skin...
5.
Settivari R, Ball N, Murphy L, Rasoulpour R, Boverhof D, Carney E
J Am Assoc Lab Anim Sci
. 2015 Apr;
54(2):214-23.
PMID: 25836969
Interest in applying 21st-century toxicity testing tools for safety assessment of industrial chemicals is growing. Whereas conventional toxicology uses mainly animal-based, descriptive methods, a paradigm shift is emerging in which...
6.
Schisler M, Sura R, Visconti N, Sosinski L, Murphy L, LeBaron M, et al.
Environ Mol Mutagen
. 2014 Jul;
55(7):530-41.
PMID: 24976023
Integrated testing strategies involve the assessment of multiple endpoints within a single toxicity study and represent an important approach for reducing animal use and streamlining testing. The present study evaluated...
7.
Froggett S, Clancy S, Boverhof D, Canady R
Part Fibre Toxicol
. 2014 Apr;
11:17.
PMID: 24708765
Advances in adding nanomaterials to various matrices have occurred in tandem with the identification of potential hazards associated with exposure to pure forms of nanomaterials. We searched multiple research publication...
8.
Gehen S, Blacker A, Boverhof D, Hanley Jr T, Hastings C, Ladics G, et al.
Crit Rev Toxicol
. 2014 Mar;
44(5):407-19.
PMID: 24601769
Conduct of a T-cell-dependent antibody response (TDAR) assay in rodents according to Environmental Protection Agency (EPA) Test Guideline OPPTS 870.7800 is now required for chemical pesticide active ingredients registered in...
9.
Kimber I, Dearman R, Basketter D, Boverhof D
Toxicology
. 2014 Feb;
318:32-9.
PMID: 24534103
Allergic sensitisation of the respiratory tract by chemicals is associated with rhinitis and asthma and remains an important occupational health issue. Although less than 80 chemicals have been confirmed as...
10.
Boverhof D, Ladics G, Luebke B, Botham J, Corsini E, Evans E, et al.
Regul Toxicol Pharmacol
. 2013 Nov;
68(1):96-107.
PMID: 24280359
As experience is gained with toxicology testing and as new assays and technologies are developed, it is critical for stakeholders to discuss opportunities to advance our overall testing strategies. To...