Darrell Desveaux
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Explore the profile of Darrell Desveaux including associated specialties, affiliations and a list of published articles.
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3534
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Recent Articles
11.
Bundalovic-Torma C, Desveaux D, Guttman D
PLoS Comput Biol
. 2022 Feb;
18(2):e1009899.
PMID: 35192600
A critical step in studying biological features (e.g., genetic variants, gene families, metabolic capabilities, or taxa) is assessing their diversity and distribution among a sample of individuals. Accurate assessments of...
12.
Seto D, Khan M, Bastedo D, Martel A, Vo T, Guttman D, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(47).
PMID: 34799454
Pathogenic effector proteins use a variety of enzymatic activities to manipulate host cellular proteins and favor the infection process. However, these perturbations can be sensed by nucleotide-binding leucine-rich-repeat (NLR) proteins...
13.
Martel A, Ruiz-Bedoya T, Breit-McNally C, Laflamme B, Desveaux D, Guttman D
Curr Opin Plant Biol
. 2021 Mar;
62:102011.
PMID: 33677388
The natural diversity of pathogen effectors and host immune components represents a snapshot of the underlying evolutionary processes driving the host-pathogen arms race. In plants, this arms race is manifested...
14.
Khan M, Subramaniam R, Desveaux D
Methods Mol Biol
. 2020 Nov;
2200:425-440.
PMID: 33175391
Proteome networks are a crucial facet of biological systems that mediate cellular functions and responses to the environment. However, a main limitation of traditional approaches to study protein interactions, such...
15.
Seto D, Laflamme B, Guttman D, Desveaux D
Plant Physiol
. 2020 Oct;
184(4):1635-1639.
PMID: 33037126
No abstract available.
16.
Martel A, Laflamme B, Seto D, Bastedo D, Dillon M, Almeida R, et al.
Front Plant Sci
. 2020 Sep;
11:1290.
PMID: 32983191
The nucleotide-binding leucine-rich repeat protein ZAR1 can recognize at least six distinct families of pathogenic effector proteins to mount an effector-triggered immune response. This remarkable immunodiversity appears to be conveyed...
17.
Laflamme B, Dillon M, Martel A, Almeida R, Desveaux D, Guttman D
Science
. 2020 Feb;
367(6479):763-768.
PMID: 32054757
Effector-triggered immunity (ETI), induced by host immune receptors in response to microbial effectors, protects plants against virulent pathogens. However, a systematic study of ETI prevalence against species-wide pathogen diversity is...
18.
Martel A, Lo T, Desveaux D, Guttman D
Mol Plant Microbe Interact
. 2019 Dec;
33(3):394-401.
PMID: 31851574
An understanding of how biological diversity affects plant-microbe interactions is becoming increasingly important, particularly with respect to components of the pathogen effector arsenal and the plant immune system. Although technological...
19.
Bastedo D, Khan M, Martel A, Seto D, Kireeva I, Zhang J, et al.
PLoS Pathog
. 2019 Jul;
15(7):e1007900.
PMID: 31269090
The Pseudomonas syringae acetyltransferase HopZ1a is delivered into host cells by the type III secretion system to promote bacterial growth. However, in the model plant host Arabidopsis thaliana, HopZ1a activity...
20.
Bastedo D, Lo T, Laflamme B, Desveaux D, Guttman D
Curr Top Microbiol Immunol
. 2019 Jun;
427:201-230.
PMID: 31240408
A broad range of Gram-negative bacteria employ a type III secretion system (T3SS) to deliver virulence proteins termed type III secreted effectors directly into the cytoplasm of eukaryotic host cells....