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Daqian Xu

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Articles 51
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Recent Articles
11.
Du L, Su Z, Wang S, Meng Y, Xiao F, Xu D, et al.
Adv Sci (Weinh) . 2023 Aug; 10(27):e2206380. PMID: 37541303
Tumor cells often overexpress immune checkpoint proteins, including CD47, for immune evasion. However, whether or how oncogenic activation of receptor tyrosine kinases, which are crucial drivers in tumor development, regulates...
12.
Wu K, Yan M, Liu T, Wang Z, Duan Y, Xia Y, et al.
Nat Cell Biol . 2023 May; 25(5):714-725. PMID: 37156912
Activation of receptor protein kinases is prevalent in various cancers with unknown impact on ferroptosis. Here we demonstrated that AKT activated by insulin-like growth factor 1 receptor signalling phosphorylates creatine...
13.
Liu T, Wang Z, Ye L, Duan Y, Jiang H, He H, et al.
Nat Cell Biol . 2023 Jan; 25(2):273-284. PMID: 36646788
Impairment of the circadian clock is linked to cancer development. However, whether the circadian clock is modulated by oncogenic receptor tyrosine kinases remains unclear. Here we demonstrated that receptor tyrosine...
14.
Wang Z, Li M, Jiang H, Luo S, Shao F, Xia Y, et al.
Nat Cell Biol . 2022 Oct; 24(11):1655-1665. PMID: 36266488
Tumour cells exhibit greater metabolic plasticity than normal cells and possess selective advantages for survival and proliferation with unclearly defined mechanisms. Here we demonstrate that glucose deprivation in normal hepatocytes...
15.
Zhao J, Shi S, Qu H, Keckesova Z, Cao Z, Yang L, et al.
Nat Metab . 2022 May; 4(6):791. PMID: 35637348
No abstract available.
16.
Li T, Dai F, He Y, Xu D, Wang R
Polymers (Basel) . 2022 Apr; 14(7). PMID: 35406334
In the Loess Plateau region, the poor structure and properties of loess slopes will cause many types of geological disasters such as landslides, mudflow, land collapse, soil erosion, and ground...
17.
Zhao J, Shi S, Qu H, Keckesova Z, Cao Z, Yang L, et al.
Nat Metab . 2022 Feb; 4(2):239-253. PMID: 35145325
Tumors can reprogram the functions of metabolic enzymes to fuel malignant growth; however, beyond their conventional functions, key metabolic enzymes have not been found to directly govern cell mitosis. Here,...
18.
Chang S, Chang M, Liu G, Xu D, Wang H, Sun R, et al.
Biomed J . 2021 Jul; 45(4):642-653. PMID: 34311128
Background: The abnormal expression of long non-coding RNA (lncRNA) Opa-interacting protein 5 antisense RNA 1 (OIP5-AS1) has been observed in many human cancers and the underlying mechanisms have been well...
19.
Shao F, Bian X, Wang J, Xu D, Guo W, Jiang H, et al.
Front Oncol . 2021 Apr; 11:561247. PMID: 33842305
Metabolic enzymes can perform non-metabolic functions and play critical roles in the regulation of a variety of important cellular activities. Phosphoenolpyruvate carboxykinase 1 (PCK1), a gluconeogenesis enzyme, was recently identified...
20.
Bian X, Liu R, Meng Y, Xing D, Xu D, Lu Z
J Exp Med . 2021 Feb; 218(1). PMID: 33601415
Dysregulation in lipid metabolism is among the most prominent metabolic alterations in cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological membranes, and signaling molecules needed for...