Danzhou Yang
Overview
Explore the profile of Danzhou Yang including associated specialties, affiliations and a list of published articles.
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84
Citations
3367
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Recent Articles
1.
Lin H, Safdar M, Washburn S, S Akhand S, Dickerhoff J, Ayers M, et al.
Commun Biol
. 2024 Aug;
7(1):963.
PMID: 39122837
Limiting cellular plasticity is of key importance for the therapeutic targeting of metastatic breast cancer (MBC). Fibroblast growth receptor (FGFR) is a critical molecule in cellular plasticity and potent inhibitors...
2.
Liu W, Zhu B, Liu L, Xia X, Jang J, Dickerhoff J, et al.
Nucleic Acids Res
. 2024 Jul;
52(16):9397-9406.
PMID: 39077944
G-quadruplex (G4) structures play integral roles in modulating biological functions and can be regulated by small molecules. The MYC gene is critical during tumor initiation and malignant progression, in which...
3.
Han Y, Buric A, Chintareddy V, DeMoss M, Chen L, Dickerhoff J, et al.
J Med Chem
. 2024 Apr;
67(9):7006-7032.
PMID: 38668707
G-quadruplexes are noncanonical four-stranded DNA secondary structures. is a master oncogene and the G-quadruplex formed in the promoter functions as a transcriptional silencer and can be stabilized by small molecules....
4.
Brundridge N, Fritz J, Dickerhoff J, Yang D, McLuckey S
J Am Soc Mass Spectrom
. 2024 Mar;
35(4):756-766.
PMID: 38456425
G-quadruplex (G4) DNA can form highly stable secondary structures in the presence of metal cations, and research has shown its potential as a transcriptional regulator for oncogenes in the human...
5.
Dickerhoff J, Jang J, Yang D
Methods
. 2023 Nov;
221:35-41.
PMID: 38029869
NMR spectroscopy is the major method for G-quadruplex structure determination under physiologically relevant solution conditions. Unlike duplex B-DNA, in which all nucleotides adopt an anti glycosidic conformation, the core tetrad-guanines...
6.
Brundridge N, Dickerhoff J, Yang D, McLuckey S
Anal Chem
. 2023 Sep;
95(40):15057-15067.
PMID: 37774231
G-quadruplex (G4) DNA is found in oncogene promoters and human telomeres and is an attractive anticancer target. Stable G4 structures form in guanine-rich sequences in the presence of metal cations...
7.
Fang S, Liu S, Yang D, Yang L, Hu C, Wan J
Front Genet
. 2022 Sep;
13:957023.
PMID: 36092921
G-quadruplex (G4) has been previously observed to be associated with gene expression. In this study, we performed integrative analysis on G4 multi-omics data from in-silicon prediction and ChIP-seq in human...
8.
Chen L, Dickerhoff J, Sakai S, Yang D
Acc Chem Res
. 2022 Sep;
55(18):2628-2646.
PMID: 36054116
DNA G-quadruplex secondary structures formed in guanine-rich human telomeres and oncogene promoters are functionally important and have emerged as a promising new class of cancer-specific drug targets. These globular intramolecular...
9.
Sakai S, Otsuka T, Matsuda S, Sakairi Y, Uchida R, Sugahara K, et al.
Anal Chem
. 2022 Apr;
94(17):6446-6450.
PMID: 35436401
Oxygen and carbon stable isotope ratios (O/O, C/C, and O/O) of CO have been crucial in helping us understand Earth and planetary systems. These ratios have also been used in...
10.
Wang K, Liu Y, Li Y, Dickerhoff J, Li J, Yang M, et al.
J Am Chem Soc
. 2022 Mar;
144(14):6361-6372.
PMID: 35352895
Guanine (G)-oxidation to 8-oxo-7,8-dihydroguanine (OG) by reactive oxygen species in genomic DNA has been implicated with various human diseases. G-quadruplex (G4)-forming sequences in gene promoters are highly susceptible to G-oxidation,...