Danny A Bitton
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Explore the profile of Danny A Bitton including associated specialties, affiliations and a list of published articles.
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29
Citations
750
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Recent Articles
11.
Sanso M, Parua P, Pinto D, Svensson J, Page V, Bitton D, et al.
Nucleic Acids Res
. 2020 Jun;
48(13):7154-7168.
PMID: 32496538
Mono-ubiquitylation of histone H2B (H2Bub1) and phosphorylation of elongation factor Spt5 by cyclin-dependent kinase 9 (Cdk9) occur during transcription by RNA polymerase II (RNAPII), and are mutually dependent in fission...
12.
Hannigan G, Prihoda D, Palicka A, Soukup J, Klempir O, Rampula L, et al.
Nucleic Acids Res
. 2019 Aug;
47(18):e110.
PMID: 31400112
Natural products represent a rich reservoir of small molecule drug candidates utilized as antimicrobial drugs, anticancer therapies, and immunomodulatory agents. These molecules are microbial secondary metabolites synthesized by co-localized genes...
13.
Grech L, Jeffares D, Sadee C, Rodriguez-Lopez M, Bitton D, Hoti M, et al.
Mol Biol Evol
. 2019 May;
36(8):1612-1623.
PMID: 31077324
The relationship between DNA sequence, biochemical function, and molecular evolution is relatively well-described for protein-coding regions of genomes, but far less clear in noncoding regions, particularly, in eukaryote genomes. In...
14.
Atkinson S, Marguerat S, Bitton D, Rodriguez-Lopez M, Rallis C, Lemay J, et al.
RNA
. 2018 Jun;
24(9):1195-1213.
PMID: 29914874
Long noncoding RNAs (lncRNAs), which are longer than 200 nucleotides but often unstable, contribute a substantial and diverse portion to pervasive noncoding transcriptomes. Most lncRNAs are poorly annotated and understood,...
15.
Malecki M, Bitton D, Rodriguez-Lopez M, Rallis C, Garcia Calavia N, Smith G, et al.
Genome Biol
. 2016 Nov;
17(1):240.
PMID: 27887640
Background: The control of energy metabolism is fundamental for cell growth and function and anomalies in it are implicated in complex diseases and ageing. Metabolism in yeast cells can be...
16.
Bitton D, Schubert F, Dey S, Okoniewski M, Smith G, Khadayate S, et al.
Front Genet
. 2015 Dec;
6:330.
PMID: 26635866
Genome-wide assays and screens typically result in large lists of genes or proteins. Enrichments of functional or other biological properties within such lists can provide valuable insights and testable hypotheses....
17.
Bitton D, Atkinson S, Rallis C, Smith G, Ellis D, Chen Y, et al.
Genome Res
. 2015 Apr;
25(6):884-96.
PMID: 25883323
Exon skipping is considered a principal mechanism by which eukaryotic cells expand their transcriptome and proteome repertoires, creating different splice variants with distinct cellular functions. Here we analyze RNA-seq data...
18.
Jeffares D, Rallis C, Rieux A, Speed D, Prevorovsky M, Mourier T, et al.
Nat Genet
. 2015 Feb;
47(3):235-41.
PMID: 25665008
Natural variation within species reveals aspects of genome evolution and function. The fission yeast Schizosaccharomyces pombe is an important model for eukaryotic biology, but researchers typically use one standard laboratory...
19.
Chen J, Beckley J, McDonald N, Ren L, Mangione M, Jang S, et al.
G3 (Bethesda)
. 2015 Jan;
5(3):361-70.
PMID: 25552606
Many fundamental biological processes are studied using the fission yeast, Schizosaccharomyces pombe. Here we report the construction of a set of 281 haploid gene deletion strains covering many previously uncharacterized...
20.
Sideri T, Rallis C, Bitton D, Lages B, Suo F, Rodriguez-Lopez M, et al.
G3 (Bethesda)
. 2014 Dec;
5(1):145-55.
PMID: 25452419
Genetic factors underlying aging are remarkably conserved from yeast to human. The fission yeast Schizosaccharomyces pombe is an emerging genetic model to analyze cellular aging. Chronological lifespan (CLS) has been...