Danny A Bitton
Overview
Explore the profile of Danny A Bitton including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
750
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Recent Articles
21.
Zilio N, Codlin S, Vashisht A, Bitton D, Head S, Wohlschlegel J, et al.
Mol Cell Biol
. 2014 Jul;
34(18):3500-14.
PMID: 25002536
The acetylation state of histones, controlled by histone acetyltransferases (HATs) and deacetylases (HDACs), profoundly affects DNA transcription and repair by modulating chromatin accessibility to the cellular machinery. The Schizosaccharomyces pombe...
22.
Bitton D, Rallis C, Jeffares D, Smith G, Chen Y, Codlin S, et al.
Genome Res
. 2014 Apr;
24(7):1169-79.
PMID: 24709818
Both canonical and alternative splicing of RNAs are governed by intronic sequence elements and produce transient lariat structures fastened by branch points within introns. To map precisely the location of...
23.
Livesay S, Collier S, Bitton D, Bahler J, Ohi M
Eukaryot Cell
. 2013 Sep;
12(11):1472-89.
PMID: 24014766
The spliceosome is a dynamic macromolecular machine that catalyzes the removal of introns from pre-mRNA, yielding mature message. Schizosaccharomyces pombe Cwf10 (homolog of Saccharomyces cerevisiae Snu114 and human U5-116K), an...
24.
Dhani D, Goult B, George G, Rogerson D, Bitton D, Miller C, et al.
Mol Biol Cell
. 2013 Sep;
24(21):3337-49.
PMID: 24006493
In humans, MOZART1 plays an essential role in mitotic spindle formation as a component of the γ-tubulin ring complex. We report that the fission yeast homologue of MOZART1, Mzt1/Tam4, is...
25.
Bitton D, Grallert A, Scutt P, Yates T, Li Y, Bradford J, et al.
Mol Syst Biol
. 2011 Dec;
7:559.
PMID: 22186733
Strand-specific RNA sequencing of S. pombe revealed a highly structured programme of ncRNA expression at over 600 loci. Waves of antisense transcription accompanied sexual differentiation. A substantial proportion of ncRNA...
26.
Bitton D, Wood V, Scutt P, Grallert A, Yates T, Smith D, et al.
Genetics
. 2011 Jan;
187(4):1207-17.
PMID: 21270388
Genome annotation is a synthesis of computational prediction and experimental evidence. Small genes are notoriously difficult to detect because the patterns used to identify them are often indistinguishable from chance...
27.
An integrated mass-spectrometry pipeline identifies novel protein coding-regions in the human genome
Bitton D, Smith D, Connolly Y, Scutt P, Miller C
PLoS One
. 2010 Feb;
5(1):e8949.
PMID: 20126623
Background: Most protein mass spectrometry (MS) experiments rely on searches against a database of known or predicted proteins, limiting their ability as a gene discovery tool. Results: Using a search...
28.
Bitton D, Okoniewski M, Connolly Y, Miller C
BMC Bioinformatics
. 2008 Feb;
9:118.
PMID: 18298841
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in part be because the different assays were...
29.
Pierce A, Unwin R, Evans C, Griffiths S, Carney L, Zhang L, et al.
Mol Cell Proteomics
. 2007 Oct;
7(5):853-63.
PMID: 17951628
There are a number of leukemogenic protein-tyrosine kinases (PTKs) associated with leukemic transformation. Although each is linked with a specific disease their functional activity poses the question whether they have...