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Danilo Basili

Explore the profile of Danilo Basili including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 88
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Recent Articles
1.
de Avila R, Muller I, Barlow H, Middleton A, Theiventhran M, Basili D, et al.
Front Toxicol . 2025 Mar; 7:1426132. PMID: 40061084
Introduction: This work evaluated a non-animal toolbox to be used within a next-generation risk assessment (NGRA) framework to assess chemical-induced lung effects using human upper and lower respiratory tract models,...
2.
Lin Z, Basili D, Chou W
Food Chem Toxicol . 2024 Jun; 190:114809. PMID: 38857761
This Special Issue contains articles on applications of various new approach methodologies (NAMs) in the field of toxicology and risk assessment. These NAMs include in vitro high-throughput screening, quantitative structure-activity...
3.
Chambers B, Basili D, Word L, Baker N, Middleton A, Judson R, et al.
Chem Res Toxicol . 2024 May; 37(6):878-893. PMID: 38736322
Adaptive stress response pathways (SRPs) restore cellular homeostasis following perturbation but may activate terminal outcomes like apoptosis, autophagy, or cellular senescence if disruption exceeds critical thresholds. Because SRPs hold the...
4.
Ruschioni S, Duca D, Tulli F, Zarantoniello M, Cardinaletti G, Corsi L, et al.
Animals (Basel) . 2024 Feb; 14(4). PMID: 38396577
is a promising insect due to its ability to convert low-value substrates as food chain by-products into highly nutritious feed. Its feeding and nutrition are important issues. The aim of...
5.
Giommi C, Lombo M, Habibi H, Rossi G, Basili D, Mangiaterra S, et al.
Sci Total Environ . 2023 Dec; 912:169303. PMID: 38135076
A plethora of studies have so far described the toxic effects of bisphenol A (BPA) on organism health, highlighting the urgent need to find new strategies not only to reduce...
6.
Harrill J, Everett L, Haggard D, Bundy J, Willis C, Shah I, et al.
Toxicology . 2023 Dec; 501:153694. PMID: 38043774
Multiple new approach methods (NAMs) are being developed to rapidly screen large numbers of chemicals to aid in hazard evaluation and risk assessments. High-throughput transcriptomics (HTTr) in human cell lines...
7.
Rivetti C, Houghton J, Basili D, Hodges G, Campos B
Environ Toxicol Chem . 2023 Mar; 42(5):1152-1166. PMID: 36861224
The last two decades have witnessed a strong momentum toward integration of cell-based and computational approaches in safety assessments. This is fueling a global regulatory paradigm shift toward reduction and...
8.
Brockmeier E, Basili D, Herbert J, Rendal C, Boakes L, Grauslys A, et al.
Sci Total Environ . 2022 Jul; 849:157666. PMID: 35908689
With the large numbers of man-made chemicals produced and released in the environment, there is a need to provide assessments on their potential effects on environmental safety and human health....
9.
Basili D, Reynolds J, Houghton J, Malcomber S, Chambers B, Liddell M, et al.
Chem Res Toxicol . 2022 Mar; 35(4):670-683. PMID: 35333521
Estimation of points of departure (PoDs) from high-throughput transcriptomic data (HTTr) represents a key step in the development of next-generation risk assessment (NGRA). Current approaches mainly rely on single key...
10.
Marisaldi L, Iorillo O, Basili D, Gioacchini G, Bobe J, Thermes V, et al.
Animals (Basel) . 2021 Dec; 11(12). PMID: 34944116
In the Mediterranean Sea, a demographic substructure of the Atlantic bluefin tuna has emerged over the last decade, with old and young individuals exhibiting different horizontal movements and spatial-temporal patterns...