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Daniil Shabashvili

Explore the profile of Daniil Shabashvili including associated specialties, affiliations and a list of published articles. Areas
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Citations 56
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Recent Articles
1.
Guijarro M, Kellish P, Dib P, Paciaroni N, Nawab A, Andring J, et al.
JCI Insight . 2023 Apr; 8(10). PMID: 37097751
Although thymidylate synthase (TYMS) inhibitors have served as components of chemotherapy regimens, the currently available inhibitors induce TYMS overexpression or alter folate transport/metabolism feedback pathways that tumor cells exploit for...
2.
Venugopal K, Feng Y, Shabashvili D, Guryanova O
Cancer Res . 2020 Oct; 81(2):254-263. PMID: 33087320
In the last decade, large-scale genomic studies in patients with hematologic malignancies identified recurrent somatic alterations in epigenetic modifier genes. Among these, the DNA methyltransferase has emerged as one of...
3.
Kellish P, Shabashvili D, Rahman M, Nawab A, Guijarro M, Zhang M, et al.
J Clin Invest . 2019 Apr; 129(6):2279-2292. PMID: 31033480
Oncolytic virotherapy has been proposed as an ablative and immunostimulatory treatment strategy for solid tumors that are resistant to immunotherapy alone; however, there is a need to optimize host immune...
4.
Park H, Shabashvili D, Nekorchuk M, Shyqyriu E, Jung J, Ladd T, et al.
J Biol Chem . 2012 Oct; 287(48):40629-40. PMID: 23043097
Background: Aβ production is influenced by intracellular trafficking of secretases and amyloid precursor protein (APP). Results: Retention in endoplasmic reticulum 1 (RER1) regulates the trafficking of γ-secretase and APP, thereby...