Danielle Brabant
Overview
Explore the profile of Danielle Brabant including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
104
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0
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Recent Articles
1.
Truong D, Boddy K, Canadien V, Brabant D, Fairn G, DCosta V, et al.
Cell Microbiol
. 2018 Jul;
20(10):e12938.
PMID: 30010242
Salmonella uses Type 3 secretion systems (T3SSs) to deliver virulence factors, called effectors, into host cells during infection. The T3SS effectors promote invasion into host cells and the generation of...
2.
Michael P, Brabant D, Bleiblo F, Ramana C, Rutherford M, Khurana S, et al.
J Thorac Dis
. 2013 Aug;
5 Suppl 2:S132-41.
PMID: 23977434
Influenza A is a negative sense single stranded RNA virus that belongs to the Orthomyxoviridae Family. This enveloped virus contains 8 segments of viral RNA which encodes 11 viral proteins....
3.
Truong D, Brabant D, Bashkurov M, Wan L, Braun V, Heo W, et al.
Cell Microbiol
. 2013 Jul;
15(12):2051-63.
PMID: 23869992
Salmonella invade host cells using Type 3 secreted effectors, which modulate host cellular targets to promote actin rearrangements at the cell surface that drive bacterial uptake. The Arp2/3 complex contributes...
4.
Bleiblo F, Michael P, Brabant D, Ramana C, Tai T, Saleh M, et al.
Int J Clin Exp Med
. 2012 Dec;
6(1):16-25.
PMID: 23236554
Discriminating the molecular patterns associated with RNA is central to innate immunity. The protein kinase PKR is a cytosolic sensor involved in the recognition of viral dsRNA and triggering interferon-induced...
5.
Bleiblo F, Michael P, Brabant D, Ramana C, Tai T, Saleh M, et al.
J Thorac Dis
. 2012 Jul;
4(2):114-25.
PMID: 22833816
Severe sepsis and the ensuing septic shock are serious life threatening conditions. These diseases are triggered by the host's over exuberant systemic response to the infecting pathogen. Several surveillance mechanisms...
6.
Bleiblo F, Michael P, Brabant D, Ramana C, Tai T, Saleh M, et al.
Int J Clin Exp Med
. 2012 Feb;
5(1):1-23.
PMID: 22328944
Sepsis and its associated syndromes represent the systemic host response to severe infection and is manifested by varying degrees of hypotension, coagulopathy, and multiorgan dysfunction. Despite great efforts being made...
7.
Brabant D, Michael P, Bleiblo F, Saleh M, Narain R, Tai T, et al.
Biochem Biophys Res Commun
. 2011 Aug;
412(2):260-5.
PMID: 21820410
Sepsis, the systemic response to infection, is the leading cause of death in the intensive care units worldwide. Septic patients can succumb through the development of early refractory hypotension or...
8.
Hussein S, Michael P, Brabant D, Omri A, Narain R, Passi K, et al.
Int J Clin Exp Med
. 2009 Aug;
2(2):131-48.
PMID: 19684886
To gain a better understanding of the gene expression changes that occurs during sepsis, we have performed a cDNA microarray study utilizing a tissue culture model that mimics human sepsis....
9.
Kumar A, Kumar A, Michael P, Brabant D, Parissenti A, Ramana C, et al.
J Biol Chem
. 2005 Oct;
280(52):42619-26.
PMID: 16223733
Proinflammatory cytokines have been linked to depression of myocardial contractility in vivo in patients with acute septic shock and in vitro models employing isolated myocytes exposed to serum from such...