Daniela Malan
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Explore the profile of Daniela Malan including associated specialties, affiliations and a list of published articles.
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53
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1311
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Recent Articles
1.
Langen J, Boyle P, Malan D, Sasse P
Sci Adv
. 2025 Feb;
11(9):eadt4103.
PMID: 40020054
Increased cardiac excitability and reduced electrical coupling promote cardiac arrhythmia and can be quantified by input resistance (), pacing threshold (), and cardiac space constant (λ). However, their measurement in...
2.
Insulin-Activated Signaling Pathway and GLUT4 Membrane Translocation in hiPSC-Derived Cardiomyocytes
Querio G, Antoniotti S, Levi R, Fleischmann B, Gallo M, Malan D
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125765
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a cell model now widely used to investigate pathophysiological features of cardiac tissue. Given the invaluable contribution hiPSC-CM could make for studies...
3.
Wietek J, Nozownik A, Pulin M, Saraf-Sinik I, Matosevich N, Gowrishankar R, et al.
Nat Methods
. 2024 May;
21(7):1275-1287.
PMID: 38811857
Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how the activity of such long-range connections contributes to behavior requires efficient methods for...
4.
Gerhards J, Volkov L, Corbo J, Malan D, Sasse P
Pflugers Arch
. 2023 Nov;
475(12):1409-1419.
PMID: 37987804
Optogenetics is a technology using light-sensitive proteins to control signaling pathways and physiological processes in cells and organs and has been applied in neuroscience, cardiovascular sciences, and many other research...
5.
Wietek J, Nozownik A, Pulin M, Saraf-Sinik I, Matosevich N, Malan D, et al.
bioRxiv
. 2023 Jul;
PMID: 37425961
Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how the activity of such long-range connections contributes to behavior requires efficient methods for...
6.
Wagdi A, Malan D, Sathyanarayanan U, Beauchamp J, Vogt M, Zipf D, et al.
Nat Commun
. 2023 Jan;
14(1):58.
PMID: 36599836
No abstract available.
7.
Benkel T, Zimmermann M, Zeiner J, Bravo S, Merten N, Lim V, et al.
Nat Commun
. 2022 Nov;
13(1):7109.
PMID: 36402762
Carvedilol is among the most effective β-blockers for improving survival after myocardial infarction. Yet the mechanisms by which carvedilol achieves this superior clinical profile are still unclear. Beyond blockade of...
8.
Wagdi A, Malan D, Sathyanarayanan U, Beauchamp J, Vogt M, Zipf D, et al.
Nat Commun
. 2022 Apr;
13(1):1765.
PMID: 35365606
G proteins are universally important for signal transduction in mammalian cells. The underlying kinetics and transformation from extracellular stimuli into intracellular signaling, however could not be investigated in detail so...
9.
Niemann P, Schiffer M, Malan D, Grunberg S, Roell W, Geisen C, et al.
Cells
. 2022 Feb;
11(4).
PMID: 35203340
Connexins (Cx) are a large family of membrane proteins that can form intercellular connections, so-called gap junctions between adjacent cells. Cx43 is widely expressed in mammals and has a variety...
10.
Cokic M, Bruegmann T, Sasse P, Malan D
Front Physiol
. 2022 Jan;
12:768495.
PMID: 34987414
G-protein signaling pathways are central in the regulation of cardiac function in physiological and pathophysiological conditions. Their functional analysis through optogenetic techniques with selective expression of opsin proteins and activation...