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Daniela Malan

Explore the profile of Daniela Malan including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 1311
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Recent Articles
11.
Monnerat G, Alarcon M, Vasconcellos L, Hochman-Mendez C, Brasil G, Bassani R, et al.
Nat Commun . 2021 Dec; 12(1):7261. PMID: 34880249
No abstract available.
12.
Rehnelt S, Malan D, Juhasz K, Wolters B, Doerr L, Beckler M, et al.
Int J Mol Sci . 2021 Jun; 22(11). PMID: 34070702
The authors wish to make the following corrections to this paper [...].
13.
Fehrentz T, Huber F, Hartrampf N, Bruegmann T, Frank J, Fine N, et al.
Nat Chem Biol . 2021 Jan; 17(3):360. PMID: 33514938
No abstract available.
14.
Lapp H, Bruegmann T, Malan D, Friedrichs S, Kilgus C, Heidsieck A, et al.
Sci Rep . 2021 Jan; 11(1):1643. PMID: 33436963
No abstract available.
15.
Funken M, Malan D, Sasse P, Bruegmann T
Front Physiol . 2019 May; 10:498. PMID: 31105593
Cardiac defibrillation to terminate lethal ventricular arrhythmia (VA) is currently performed by applying high energy electrical shocks. In cardiac tissue, electrical shocks induce simultaneously de- and hyperpolarized areas and only...
16.
Makowka P, Bruegmann T, Dusend V, Malan D, Beiert T, Hesse M, et al.
Nat Commun . 2019 Mar; 10(1):1281. PMID: 30894542
The standard technique for investigating adrenergic effects on heart function is perfusion with pharmaceutical agonists, which does not provide high temporal or spatial precision. Herein we demonstrate that the light...
17.
Fehrentz T, Huber F, Hartrampf N, Bruegmann T, Frank J, Fine N, et al.
Nat Chem Biol . 2018 Jul; 14(8):764-767. PMID: 30013061
L-type Ca channels (LTCCs) play a crucial role in excitation-contraction coupling and release of hormones from secretory cells. They are targets of antihypertensive and antiarrhythmic drugs such as diltiazem. Here,...
18.
Rehnelt S, Malan D, Juhasz K, Wolters B, Doerr L, Beckler M, et al.
Int J Mol Sci . 2017 Dec; 18(12). PMID: 29211031
Side effects on cardiac ion channels causing lethal arrhythmias are one major reason for drug withdrawals from the market. Field potential (FP) recording from cardiomyocytes, is a well-suited tool to...
19.
Lapp H, Bruegmann T, Malan D, Friedrichs S, Kilgus C, Heidsieck A, et al.
Sci Rep . 2017 Aug; 7(1):9629. PMID: 28851973
Side effects on cardiac ion channels are one major reason for new drugs to fail during preclinical evaluation. Herein we propose a simple optogenetic screening tool measuring extracellular field potentials...
20.
Jara-Avaca M, Kempf H, Ruckert M, Robles-Diaz D, Franke A, de la Roche J, et al.
Stem Cell Reports . 2017 Jan; 8(2):305-317. PMID: 28089668
Subtype-specific human cardiomyocytes (CMs) are valuable for basic and applied research. Induction of cardiomyogenesis and enrichment of nodal-like CMs was described for mouse pluripotent stem cells (mPSCs) in response to...