Daniela C Soto
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Explore the profile of Daniela C Soto including associated specialties, affiliations and a list of published articles.
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23
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1767
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Recent Articles
1.
Soto D, Uribe-Salazar J, Kaya G, Valdarrago R, Sekar A, Haghani N, et al.
bioRxiv
. 2024 Oct;
PMID: 39386494
Genomic drivers of human-specific neurological traits remain largely undiscovered. Duplicated genes expanded uniquely in the human lineage likely contributed to brain evolution, including the increased complexity of synaptic connections between...
2.
Uribe-Salazar J, Kaya G, Weyenberg K, Radke B, Hino K, Soto D, et al.
bioRxiv
. 2024 Sep;
PMID: 39314374
The expansion of the human family, resulting in a human-specific paralog likely contributed to altered evolutionary brain features. The introduction of in mouse models is associated with changes in cortical...
3.
Gutierrez Fugon O, Sharifi O, Heath N, Soto D, Gomez J, Yasui D, et al.
Hum Mol Genet
. 2024 Jul;
33(19):1711-1725.
PMID: 39045627
Human cell line models, including the neuronal precursor line LUHMES, are important for investigating developmental transcriptional dynamics within imprinted regions, particularly the 15q11-q13 Angelman (AS) and Prader-Willi (PWS) syndrome locus....
4.
Ostridge H, Fontsere C, Lizano E, Soto D, Schmidt J, Saxena V, et al.
bioRxiv
. 2024 Jul;
PMID: 39026872
How populations adapt to their environment is a fundamental question in biology. Yet we know surprisingly little about this process, especially for endangered species such as non-human great apes. Chimpanzees,...
5.
Chen P, Chen R, LaPierre N, Chen Z, Mefford J, Marcus E, et al.
Cell Genom
. 2024 May;
4(5):100545.
PMID: 38697120
Knowing the genes involved in quantitative traits provides an entry point to understanding the biological bases of behavior, but there are very few examples where the pathway from genetic locus...
6.
Gutierrez Fugon O, Sharifi O, Heath N, Soto D, Gomez J, Yasui D, et al.
bioRxiv
. 2024 Apr;
PMID: 38586056
Human cell line models, including the neuronal precursor line LUHMES, are important for investigating developmental transcriptional dynamics within imprinted regions, particularly the 15q11-q13 Angelman (AS) and Prader-Willi (PWS) syndrome locus....
7.
Chen P, Chen R, LaPierre N, Chen Z, Mefford J, Marcus E, et al.
bioRxiv
. 2024 Jan;
PMID: 38260483
Knowing the genes involved in quantitative traits provides a critical entry point to understanding the biological bases of behavior, but there are very few examples where the pathway from genetic...
8.
Libe-Philippot B, Lejeune A, Wierda K, Louros N, Erkol E, Vlaeminck I, et al.
Cell
. 2023 Dec;
186(26):5766-5783.e25.
PMID: 38134874
The enhanced cognitive abilities characterizing the human species result from specialized features of neurons and circuits. Here, we report that the hominid-specific gene LRRC37B encodes a receptor expressed in human...
9.
Behera S, LeFaive J, Orchard P, Mahmoud M, Paulin L, Farek J, et al.
Genome Biol
. 2023 Feb;
24(1):31.
PMID: 36810122
The current version of the human reference genome, GRCh38, contains a number of errors including 1.2 Mbp of falsely duplicated and 8.04 Mbp of collapsed regions. These errors impact the...
10.
Soto D, Uribe-Salazar J, Shew C, Sekar A, McGinty S, Dennis M
Am J Biol Anthropol
. 2023 Feb;
181 Suppl 76:118-144.
PMID: 36794631
Structural variants (SVs)-including duplications, deletions, and inversions of DNA-can have significant genomic and functional impacts but are technically difficult to identify and assay compared with single-nucleotide variants. With the aid...