Daniela Bertinetti
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Explore the profile of Daniela Bertinetti including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
707
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Recent Articles
1.
Oz S, Keren-Raifman T, Sharon T, Subramaniam S, Pallien T, Katz M, et al.
BMC Biol
. 2024 Nov;
22(1):276.
PMID: 39609812
Background: The β-adrenergic augmentation of cardiac contraction, by increasing the conductivity of L-type voltage-gated Ca1.2 channels, is of great physiological and pathophysiological importance. Stimulation of β-adrenergic receptors (βAR) activates protein...
2.
Steiner W, Iverson N, Venkatakrishnan V, Wu J, Stepniewski T, Michaelson Z, et al.
bioRxiv
. 2024 Nov;
PMID: 39554190
The Hedgehog (Hh) signaling pathway is fundamental to embryogenesis, tissue homeostasis, and cancer. Hh signals are transduced via an unusual mechanism: upon agonist-induced phosphorylation, the noncanonical G protein-coupled receptor SMOOTHENED...
3.
Stormer E, Weng J, Wu J, Bertinetti D, Sharma P, Ma W, et al.
Biochem J
. 2023 May;
PMID: 37212165
LRRK2 is a multi-domain protein with three catalytically inert N-terminal domains (NtDs) and four C-terminal domains, including a kinase and a GTPase domain. LRRK2 mutations are linked to Parkinson's Disease....
4.
Happ J, Arveseth C, Bruystens J, Bertinetti D, Nelson I, Olivieri C, et al.
Nat Struct Mol Biol
. 2022 Oct;
29(10):990-999.
PMID: 36202993
The Hedgehog (Hh) cascade is central to development, tissue homeostasis and cancer. A pivotal step in Hh signal transduction is the activation of glioma-associated (GLI) transcription factors by the atypical...
5.
Reginka M, Hoang H, Efendi O, Merkel M, Huhnstock R, Holzinger D, et al.
Langmuir
. 2021 Jul;
37(28):8498-8507.
PMID: 34231364
Controlled transport of surface-functionalized magnetic beads in a liquid medium is a central requirement for the handling of captured biomolecular targets in microfluidic lab-on-chip biosensors. Here, the influence of the...
6.
Lasonder E, More K, Singh S, Haidar M, Bertinetti D, Kennedy E, et al.
Front Microbiol
. 2021 Jun;
12:684005.
PMID: 34108954
We review the role of signaling pathways in regulation of the key processes of merozoite egress and red blood cell invasion by and, in particular, the importance of the second...
7.
Palencia-Campos A, Aoto P, Machal E, Rivera-Barahona A, Soto-Bielicka P, Bertinetti D, et al.
Am J Hum Genet
. 2020 Oct;
107(5):977-988.
PMID: 33058759
PRKACA and PRKACB code for two catalytic subunits (Cα and Cβ) of cAMP-dependent protein kinase (PKA), a pleiotropic holoenzyme that regulates numerous fundamental biological processes such as metabolism, development, memory,...
8.
Knape M, Wallbott M, Burghardt N, Bertinetti D, Hornung J, Schmidt S, et al.
Cells
. 2020 Jul;
9(6).
PMID: 32630525
cAMP-dependent protein kinase (PKA) is the major receptor of the second messenger cAMP and a prototype for Ser/Thr-specific protein kinases. Although PKA strongly prefers serine over threonine substrates, little is...
9.
Manschwetus J, Wallbott M, Fachinger A, Obergruber C, Pautz S, Bertinetti D, et al.
Front Neurosci
. 2020 Apr;
14:302.
PMID: 32317922
Proteins of the 14-3-3 family are well known modulators of the leucine-rich repeat kinase 2 (LRRK2) regulating kinase activity, cellular localization, and ubiquitylation. Although binding between those proteins has been...
10.
Lelle M, Otte M, Thon S, Bertinetti D, Herberg F, Benndorf K
Bioorg Med Chem
. 2019 Mar;
27(8):1704-1713.
PMID: 30879860
Synthetic derivatives of cyclic adenosine monophosphate, such as halogenated or other more hydrophobic analogs, are widely used compounds, to investigate diverse signal transduction pathways of eukaryotic cells. This inspired us...