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Daniel Weissberger

Explore the profile of Daniel Weissberger including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 34
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Recent Articles
1.
Weissberger D, Stenzel M, Hunter L
Molecules . 2024 Oct; 29(20). PMID: 39459317
Covalent drugs can offer significant advantages over non-covalent drugs in terms of pharmacodynamics (i.e., target-binding properties). However, the development of covalent drugs is sometimes hampered by pharmacokinetic limitations (e.g., low...
2.
Richardson N, OMalley L, Weissberger D, Tumber A, Schofield C, Griffith R, et al.
Bioorg Med Chem . 2021 Apr; 38:116115. PMID: 33862469
Prolyl hydroxylase (PHD) enzymes play a critical role in the cellular responses to hypoxia through their regulation of the hypoxia inducible factor α (HIF-α) transcription factors. PHD inhibitors show promise...
3.
Pang C, Ballouz S, Weissberger D, Thibaut L, Hamey J, Gillis J, et al.
Mol Cell Proteomics . 2020 Aug; 19(11):1876-1895. PMID: 32817346
Co-fractionation MS (CF-MS) is a technique with potential to characterize endogenous and unmanipulated protein complexes on an unprecedented scale. However this potential has been offset by a lack of guidelines...
4.
Jwad R, Weissberger D, Hunter L
Chem Rev . 2020 Aug; 120(17):9743-9789. PMID: 32786420
Cyclic peptides are promising scaffolds for drug development, attributable in part to their increased conformational order compared to linear peptides. However, when optimizing the target-binding or pharmacokinetic properties of cyclic...