Daniel V Sietsema
Overview
Explore the profile of Daniel V Sietsema including associated specialties, affiliations and a list of published articles.
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4
Citations
91
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Recent Articles
1.
Cyr P, Fader L, Burch J, Pike K, Sietsema D, Boily M, et al.
ACS Med Chem Lett
. 2024 Dec;
15(12):2201-2209.
PMID: 39691514
Using a high-throughput screening (HTS) approach, a new GTP-site binding pyridine-carboxylate series of cGAS inhibitors was discovered. The biochemical potency of this new pyridine carboxylate series was improved 166-fold from...
2.
Mangan A, Sietsema D, Li D, Moore J, Citi S, Prekeris R
Nat Commun
. 2016 Aug;
7:12426.
PMID: 27484926
Coordinated polarization of epithelial cells is a key step during morphogenesis that leads to the formation of an apical lumen. Rab11 and its interacting protein FIP5 are necessary for the...
3.
Gartz Hanson M, Aiken J, Sietsema D, Sept D, Bates E, Niswander L, et al.
Dev Biol
. 2015 Dec;
409(2):406-19.
PMID: 26658218
Mutations in the microtubule cytoskeleton are linked to cognitive and locomotor defects during development, and neurodegeneration in adults. How these mutations impact microtubules, and how this alters function at the...
4.
Kirby K, Marchand B, Ong Y, Ndongwe T, Hachiya A, Michailidis E, et al.
Antimicrob Agents Chemother
. 2012 Jan;
56(4):2048-61.
PMID: 22252812
RNase H inhibitors (RNHIs) have gained attention as potential HIV-1 therapeutics. Although several RNHIs have been studied in the context of HIV-1 reverse transcriptase (RT) RNase H, there is no...