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Daniel Ssozi

Explore the profile of Daniel Ssozi including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 93
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Recent Articles
1.
Weng C, Yu F, Yang D, Poeschla M, Liggett L, Jones M, et al.
Nature . 2024 Jan; 627(8003):389-398. PMID: 38253266
The human blood system is maintained through the differentiation and massive amplification of a limited number of long-lived haematopoietic stem cells (HSCs). Perturbations to this process underlie diverse diseases, but...
2.
Griffin G, Booth C, Togami K, Chung S, Ssozi D, Verga J, et al.
Nature . 2023 Jun; 618(7966):834-841. PMID: 37286599
Tumours most often arise from progression of precursor clones within a single anatomical niche. In the bone marrow, clonal progenitors can undergo malignant transformation to acute leukaemia, or differentiate into...
3.
DePasquale E, Ssozi D, Ainciburu M, Good J, Noel J, Villanueva M, et al.
Front Immunol . 2022 Apr; 13:809414. PMID: 35359938
The immune system represents a major barrier to cancer progression, driving the evolution of immunoregulatory interactions between malignant cells and T-cells in the tumor environment. Blastic plasmacytoid dendritic cell neoplasm...
4.
Miller T, Lareau C, Verga J, DePasquale E, Liu V, Ssozi D, et al.
Nat Biotechnol . 2022 Feb; 40(7):1030-1034. PMID: 35210612
The combination of single-cell transcriptomics with mitochondrial DNA variant detection can be used to establish lineage relationships in primary human cells, but current methods are not scalable to interrogate complex...
5.
Acosta J, Ssozi D, van Galen P
Arterioscler Thromb Vasc Biol . 2021 Jan; 41(3):1012-1018. PMID: 33441024
The blood system is often represented as a tree-like structure with stem cells that give rise to mature blood cell types through a series of demarcated steps. Although this representation...