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Daniel Spindlow

Explore the profile of Daniel Spindlow including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 384
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Recent Articles
1.
Kinoshita M, Kobayashi T, Planells B, Klisch D, Spindlow D, Masaki H, et al.
Development . 2021 Dec; 148(23). PMID: 34874452
Despite four decades of effort, robust propagation of pluripotent stem cells from livestock animals remains challenging. The requirements for self-renewal are unclear and the relationship of cultured stem cells to...
2.
Kinoshita M, Barber M, Mansfield W, Cui Y, Spindlow D, Stirparo G, et al.
Cell Stem Cell . 2021 Dec; 28(12):2180. PMID: 34861148
No abstract available.
3.
Yanagida A, Spindlow D, Nichols J, Dattani A, Smith A, Guo G
Cell Stem Cell . 2021 May; 28(6):1016-1022.e4. PMID: 33957081
Human naive pluripotent cells can differentiate into extraembryonic trophectoderm and hypoblast. Here we describe a human embryo model (blastoid) generated by self-organization. Brief induction of trophectoderm leads to formation of...
4.
Guo G, Stirparo G, Strawbridge S, Spindlow D, Yang J, Clarke J, et al.
Cell Stem Cell . 2021 Apr; 28(6):1040-1056.e6. PMID: 33831366
Classic embryological experiments have established that the early mouse embryo develops via sequential lineage bifurcations. The first segregated lineage is the trophectoderm, essential for blastocyst formation. Mouse naive epiblast and...
5.
Kinoshita M, Barber M, Mansfield W, Cui Y, Spindlow D, Stirparo G, et al.
Cell Stem Cell . 2020 Dec; 28(3):453-471.e8. PMID: 33271069
Pluripotent cells emerge as a naive founder population in the blastocyst, acquire capacity for germline and soma formation, and then undergo lineage priming. Mouse embryonic stem cells (ESCs) and epiblast-derived...