Thomas H Winkler
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Explore the profile of Thomas H Winkler including associated specialties, affiliations and a list of published articles.
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87
Citations
3696
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Recent Articles
1.
Chege Kuria T, Schneider A, Baraka F, Wanzek J, Vogg L, Brey S, et al.
Front Immunol
. 2024 Nov;
15:1473760.
PMID: 39483469
The germinal center (GC) reaction is crucial for somatic hypermutation, affinity maturation, and the selection of high-affinity B cells, all of which are hallmarks of the humoral immune response. Understanding...
2.
Vogg L, Winkler T
Eur J Immunol
. 2024 Aug;
54(11):e2451076.
PMID: 39136644
The intestinal epithelium harbours a unique lymphocyte population, the intraepithelial lymphocytes (IELs). A large fraction of IELs is represented by γδ T cells. Their role in epithelial homeostasis and immune...
3.
Liang C, Spoerl S, Xiao Y, Habenicht K, Haeusl S, Sandner I, et al.
Commun Biol
. 2024 Jul;
7(1):879.
PMID: 39025930
In clinical situations, peripheral blood accessible CD3CD4CXCR5 T-follicular helper (T) cells may have to serve as a surrogate indicator for dysregulated germinal center responses in tissues. To determine the heterogeneity...
4.
Bootz A, Reuter N, Nimmerjahn F, Britt W, Mach M, Winkler T
Eur J Immunol
. 2024 Jul;
54(10):e2451044.
PMID: 39014923
Human cytomegalovirus is a medically important pathogen. Previously, using murine CMV (MCMV), we provided evidence that both neutralizing and nonneutralizing antibodies can confer protection from viral infection in vivo. In...
5.
Stahl-Hennig C, Peter A, Cordsmeier A, Stolte-Leeb N, Vestweber R, Socher E, et al.
J Virol
. 2024 Jun;
98(7):e0062824.
PMID: 38899895
The potency of antibody neutralization in cell culture has been used as the key criterion for selection of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for clinical development....
6.
Montorsi L, Pitcher M, Zhao Y, Dionisi C, Demonti A, Tull T, et al.
Nat Commun
. 2024 May;
15(1):4051.
PMID: 38744839
Intestinal homeostasis is maintained by the response of gut-associated lymphoid tissue to bacteria transported across the follicle associated epithelium into the subepithelial dome. The initial response to antigens and how...
7.
Winkler J, Tittlbach H, Schneider A, Vasova I, Strobel J, Herold S, et al.
Blood Adv
. 2024 Mar;
8(10):2373-2383.
PMID: 38467031
Immune reconstitution after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is slow and patients carry a high and prolonged risk of opportunistic infections. We hypothesized that the adoptive transfer of donor...
8.
Kocher K, Moosmann C, Drost F, Schulein C, Irrgang P, Steininger P, et al.
Lancet Infect Dis
. 2024 Mar;
24(5):e272-e274.
PMID: 38452777
No abstract available.
9.
Rauch E, Amendt T, Lopez Krol A, Lang F, Linse V, Hohmann M, et al.
Nat Commun
. 2024 Feb;
15(1):1229.
PMID: 38336876
Endogenous retroviruses (ERVs) are an integral part of the mammalian genome. The role of immune control of ERVs in general is poorly defined as is their function as anti-cancer immune...
10.
Elrod J, Heuer A, Knopf J, Schoen J, Schonfeld L, Trochimiuk M, et al.
iScience
. 2023 Nov;
26(12):108289.
PMID: 38034352
Peritoneal adhesions are poorly understood but highly prevalent conditions that can cause intestinal obstruction and pelvic pain requiring surgery. While there is consensus that stress-induced inflammation triggers peritoneal adhesions, the...