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Daniel Pulido

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Articles 26
Citations 185
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Recent Articles
1.
Tomsen-Melero J, Molto-Abad M, Merlo-Mas J, Diaz-Riascos Z, Cristobal-Lecina E, Soldevila A, et al.
Sci Adv . 2024 Dec; 10(50):eadq4738. PMID: 39671483
The central nervous system represents a major target tissue for therapeutic approach of numerous lysosomal storage disorders. Fabry disease arises from the lack or dysfunction of the lysosomal alpha-galactosidase A...
2.
Martinez-Miguel M, Castellote-Borrell M, Kober M, Kyvik A, Tomsen-Melero J, Vargas-Nadal G, et al.
ACS Appl Mater Interfaces . 2022 Oct; 14(42):48179-48193. PMID: 36251059
The synthesis and study of the tripeptide Arg-Gly-Asp (RGD), the binding site of different extracellular matrix proteins, e.g., fibronectin and vitronectin, has allowed the production of a wide range of...
3.
Pulido D, Casado-Anguera V, Gomez-Autet M, Llopart N, Moreno E, Casajuana-Martin N, et al.
J Med Chem . 2022 Jan; 65(1):616-632. PMID: 34982555
A G protein-coupled receptor heteromer that fulfills the established criteria for its existence is the complex between adenosine A (AR) and dopamine D (DR) receptors. Here, we have designed and...
4.
Merlo-Mas J, Tomsen-Melero J, Corchero J, Gonzalez-Mira E, Font A, Pedersen J, et al.
J Supercrit Fluids . 2021 Jul; 173:105204. PMID: 34219919
Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads...
5.
Tomsen-Melero J, Passemard S, Garcia-Aranda N, Diaz-Riascos Z, Gonzalez-Rioja R, Pedersen J, et al.
ACS Appl Mater Interfaces . 2021 Feb; 13(7):7825-7838. PMID: 33583172
Fabry disease is a rare lysosomal storage disorder characterized by a deficiency of α-galactosidase A (GLA), a lysosomal hydrolase. The enzyme replacement therapy administering naked GLA shows several drawbacks including...
6.
Zhang S, Lloveras V, Pulido D, Liko F, Pinto L, Albericio F, et al.
Pharmaceutics . 2020 Aug; 12(8). PMID: 32823903
Finding alternatives to gadolinium (Gd)-based contrast agents (CA) with the same or even better paramagnetic properties is crucial to overcome their established toxicity. Herein we describe the synthesis and characterization...
7.
Cristobal-Lecina E, Pulido D, Martin-Malpartida P, Macias M, Albericio F, Royo M
ACS Omega . 2020 Mar; 5(10):5508-5519. PMID: 32201843
A method for conjugating cholesterol to peptide ligands through non-disperse polyethylene glycol (ND-PEG) through a non-hydrolysable linkage is described. The iterative addition of tetraethylene glycol macrocyclic sulfate to cholesterol (Chol)...
8.
Pesarrodona M, Sanchez-Garcia L, Seras-Franzoso J, Sanchez-Chardi A, Balta-Foix R, Camara-Sanchez P, et al.
ACS Appl Mater Interfaces . 2019 Dec; 12(5):5381-5388. PMID: 31840972
Five peptide ligands of four different cell surface receptors (nucleolin, CXCR1, CMKLR1, and CD44v6) have been evaluated as targeting moieties for triple-negative human breast cancers. Among them, the peptide F3,...
9.
Fernandez J, Acosta G, Pulido D, Maly M, Copa-Patino J, Soliveri J, et al.
Mol Pharm . 2019 Apr; 16(6):2661-2674. PMID: 31009225
Over the last decades, multidrug-resistant bacteria have emerged and spread, increasing the number of bacteria, against which commonly used antibiotics are no longer effective. It has become a serious public...
10.
Pulido D, Casado-Anguera V, Perez-Benito L, Moreno E, Cordomi A, Lopez L, et al.
J Med Chem . 2018 Sep; 61(20):9335-9346. PMID: 30257092
Bivalent ligands have emerged as chemical tools to study G protein-coupled receptor dimers. Using a combination of computational, chemical, and biochemical tools, here we describe the design of bivalent ligand...