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Daniel Paull

Explore the profile of Daniel Paull including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 1428
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Recent Articles
1.
Comolet G, Bose N, Winchell J, Duren-Lubanski A, Rusielewicz T, Goldberg J, et al.
iScience . 2024 Dec; 27(12):111434. PMID: 39720532
Applying artificial intelligence (AI) to image-based morphological profiling cells offers significant potential for identifying disease states and drug responses in high-content imaging (HCI) screens. When differences between populations (e.g., healthy...
2.
Seah C, Breen M, Rusielewicz T, Bader H, Xu C, Hunter C, et al.
Nat Neurosci . 2024 Dec; 28(1):214. PMID: 39633181
No abstract available.
3.
Wesely J, Rusielewicz T, Chen Y, Hartley B, McKenzie D, Yim M, et al.
bioRxiv . 2024 Oct; PMID: 39386428
Amino-terminal (Nt-) acetylation (NTA) is a common protein modification, affecting 80% of cytosolic proteins in humans. The human essential gene, encodes the enzyme NAA10, as the catalytic subunit for the...
4.
Clayton B, Barbar L, Sapar M, Kalpana K, Rao C, Migliori B, et al.
Cell Stem Cell . 2024 Aug; 31(11):1701-1713.e8. PMID: 39191254
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system (CNS), resulting in neurological disability that worsens over time. While progress has been made in defining...
5.
Seah C, Signer R, Deans M, Bader H, Rusielewicz T, Hicks E, et al.
bioRxiv . 2024 Jan; PMID: 38234801
To explain why individuals exposed to identical stressors experience divergent clinical outcomes, we determine how molecular encoding of stress modifies genetic risk for brain disorders. Analysis of post-mortem brain (n=304)...
6.
Hall J, Daniszewski M, Cheung S, Shobhana K, Kumar H, Liang H, et al.
SLAS Technol . 2023 Sep; 29(3):100106. PMID: 37657710
Age-Related Macular Degeneration (AMD) is a highly prevalent form of retinal disease amongst Western communities over 50 years of age. A hallmark of AMD pathogenesis is the accumulation of drusen...
7.
Clayton B, Barbar L, Sapar M, Rusielewicz T, Kalpana K, Migliori B, et al.
bioRxiv . 2023 Aug; PMID: 37577713
Multiple sclerosis (MS) is considered an inflammatory and neurodegenerative disease of the central nervous system, typically resulting in significant neurological disability that worsens over time. While considerable progress has been...
8.
Winchell J, Comolet G, Buckley-Herd G, Hutson D, Bose N, Paull D, et al.
SLAS Discov . 2023 Aug; 28(7):306-315. PMID: 37573010
The increasing use of automation in cellular assays and cell culture presents significant opportunities to enhance the scale and throughput of imaging assays, but to do so, reliable data quality...
9.
Yang L, Han Y, Zhou T, Lacko L, Saeed M, Tan C, et al.
iScience . 2023 Aug; 26(7):107001. PMID: 37534130
Population-based genome-wide association studies (GWAS) normally require a large sample size, which can be labor intensive and costly. Recently, we reported a human induced pluripotent stem cell (hiPSC) array-based GWAS...
10.
Seah C, Breen M, Rusielewicz T, Bader H, Xu C, Hunter C, et al.
Nat Neurosci . 2022 Oct; 25(11):1434-1445. PMID: 36266471
Post-traumatic stress disorder (PTSD) can develop following severe trauma, but the extent to which genetic and environmental risk factors contribute to individual clinical outcomes is unknown. Here, we compared transcriptional...