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Daniel Olal

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Articles 8
Citations 155
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Recent Articles
1.
Dick A, Mikirtumov V, Fuchs J, Krupp F, Olal D, Bendl E, et al.
Structure . 2024 May; 32(8):1068-1078.e5. PMID: 38749445
Orthomyxoviruses, such as influenza and thogotoviruses, are important human and animal pathogens. Their segmented viral RNA genomes are wrapped by viral nucleoproteins (NPs) into helical ribonucleoprotein complexes (RNPs). NP structures...
2.
Nickl P, Hilal T, Olal D, Donskyi I, Radnik J, Ludwig K, et al.
Small . 2022 Dec; 19(8):e2205932. PMID: 36507556
Protein adsorption at the air-water interface is a serious problem in cryogenic electron microscopy (cryoEM) as it restricts particle orientations in the vitrified ice-film and promotes protein denaturation. To address...
3.
Sahtoe D, Coscia A, Mustafaoglu N, Miller L, Olal D, Vulovic I, et al.
Proc Natl Acad Sci U S A . 2021 Apr; 118(17). PMID: 33879614
The de novo design of polar protein-protein interactions is challenging because of the thermodynamic cost of stripping water away from the polar groups. Here, we describe a general approach for...
4.
Olal D, Daumke O
Cell Rep . 2016 Mar; 14(9):2092-2099. PMID: 26923588
Hantaviruses are etiological agents of life-threatening hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. The nucleoprotein (N) of hantavirus is essential for viral transcription and replication, thus representing an...
5.
Oden F, Marino S, Brand J, Scheu S, Kriegel C, Olal D, et al.
Mol Oncol . 2015 May; 9(7):1348-58. PMID: 25953704
Multiple myeloma (MM) is an aggressive incurable plasma cell malignancy with a median life expectancy of less than seven years. Antibody-based therapies have demonstrated substantial clinical benefit for patients with...
6.
Dick A, Graf L, Olal D, von der Malsburg A, Gao S, Kochs G, et al.
J Biol Chem . 2015 Apr; 290(20):12779-92. PMID: 25829498
Myxovirus resistance (Mx) GTPases are induced by interferon and inhibit multiple viruses, including influenza and human immunodeficiency viruses. They have the characteristic domain architecture of dynamin-related proteins with an N-terminal...
7.
Olal D, Dick A, Woods Jr V, Liu T, Li S, Devignot S, et al.
Nucleic Acids Res . 2014 Apr; 42(9):6025-37. PMID: 24688060
Toscana virus is an emerging bunyavirus in Mediterranean Europe where it accounts for 80% of pediatric meningitis cases during the summer. The negative-strand ribonucleic acid (RNA) genome of the virus...
8.
Olal D, Kuehne A, Bale S, Halfmann P, Hashiguchi T, Fusco M, et al.
J Virol . 2011 Dec; 86(5):2809-16. PMID: 22171276
Antibody 14G7 is protective against lethal Ebola virus challenge and recognizes a distinct linear epitope in the prominent mucin-like domain of the Ebola virus glycoprotein GP. The structure of 14G7...