Daniel Menendez
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Explore the profile of Daniel Menendez including associated specialties, affiliations and a list of published articles.
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43
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1631
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Recent Articles
11.
Lowe J, Nguyen T, Grimm S, Gabor K, Peddada S, Li L, et al.
Cell Death Differ
. 2016 Nov;
24(1):181-191.
PMID: 27834950
Tumor necrosis factor-α-induced protein 8 (TNFAIP8) is a stress-response gene that has been associated with cancer, but no studies have differentiated among or defined the regulation or function of any...
12.
Menendez D, Lowe J, Snipe J, Resnick M
Oncotarget
. 2016 Aug;
7(38):61630-61642.
PMID: 27533082
Diversity within the p53 transcriptional network can arise from a matrix of changes that include target response element sequences and p53 expression level variations. We previously found that wild type...
13.
Currier J, Cheng W, Menendez D, Conolly R, Chorley B
PLoS One
. 2016 May;
11(5):e0155875.
PMID: 27195669
Determining mechanism-based biomarkers that distinguish adaptive and adverse cellular processes is critical to understanding the health effects of environmental exposures. Shifting from in vivo, low-throughput toxicity studies to high-throughput screening...
14.
Shatz M, Shats I, Menendez D, Resnick M
Oncotarget
. 2015 Jul;
6(19):16963-80.
PMID: 26220208
The p53 tumor suppressor regulates transcription of genes associated with diverse cellular functions including apoptosis, growth arrest, DNA repair and differentiation. Recently, we established that p53 can modulate expression of...
15.
Lowe J, Menendez D, Fessler M
Cell Cycle
. 2014 Dec;
13(19):2983-4.
PMID: 25486553
No abstract available.
16.
17.
Lowe J, Menendez D, Bushel P, Shatz M, Kirk E, Troester M, et al.
Cancer Res
. 2014 Apr;
74(8):2182-92.
PMID: 24737129
Macrophages are sentinel immune cells that survey the tissue microenvironment, releasing cytokines in response to both exogenous insults and endogenous events such as tumorigenesis. Macrophages mediate tumor surveillance and therapy-induced...
18.
Nguyen T, Menendez D, Resnick M, Anderson C
Hum Mutat
. 2014 Jan;
35(6):738-55.
PMID: 24395704
The wild-type (WT) human p53 (TP53) tumor suppressor can be posttranslationally modified at over 60 of its 393 residues. These modifications contribute to changes in TP53 stability and in its...
19.
Ciribilli Y, Monti P, Bisio A, Nguyen H, Ethayathulla A, Ramos A, et al.
Nucleic Acids Res
. 2013 Jul;
41(18):8637-53.
PMID: 23892287
Structural and biochemical studies have demonstrated that p73, p63 and p53 recognize DNA with identical amino acids and similar binding affinity. Here, measuring transactivation activity for a large number of...
20.
Menendez D, Nguyen T, Freudenberg J, Mathew V, Anderson C, Jothi R, et al.
Nucleic Acids Res
. 2013 Jun;
41(15):7286-301.
PMID: 23775793
The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have taken a comprehensive approach to characterizing the human p53...