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Daniel Malouli

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Articles 35
Citations 1172
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Recent Articles
1.
Wang H, Taher H, Kreklywich C, Schmidt K, Scheef E, Barfield R, et al.
Sci Transl Med . 2025 Mar; 17(789):eadm8961. PMID: 40073152
Congenital cytomegalovirus (cCMV) is the leading infectious cause of neonatal neurological impairment worldwide, but the viral factors enabling vertical spread across the placenta remain undetermined. The pentameric complex (PC), composed...
2.
Otero C, Petkova S, Ebermann M, Taher H, John N, Hoffmann K, et al.
Nat Commun . 2025 Jan; 16(1):1200. PMID: 39885150
Human cytomegalovirus (HCMV) encodes four viral Fc-gamma receptors (vFcγRs) that counteract antibody-mediated activation in vitro, but their role in infection and pathogenesis is unknown. To examine their in vivo function...
3.
Malouli D, Taher H, Mansouri M, Iyer R, Reed J, Papen C, et al.
Sci Immunol . 2024 Oct; 9(100):eadp5216. PMID: 39392895
Rhesus cytomegalovirus (RhCMV) vectors elicit major histocompatibility complex (MHC)-E-restricted CD8 T cells that stringently control simian immunodeficiency virus (SIV) in rhesus macaques. These responses require deletion of eight RhCMV chemokine-like...
4.
Malouli D, Tiwary M, Gilbride R, Morrow D, Hughes C, Selseth A, et al.
Nat Commun . 2024 Jul; 15(1):6007. PMID: 39030218
An influenza vaccine approach that overcomes the problem of viral sequence diversity and provides long-lived heterosubtypic protection is urgently needed to protect against pandemic influenza viruses. Here, to determine if...
5.
Iyer R, Verweij M, Nair S, Morrow D, Mansouri M, Chakravarty D, et al.
Sci Adv . 2024 May; 10(19):eadm7515. PMID: 38728394
The nonpolymorphic major histocompatibility complex E (MHC-E) molecule is up-regulated on many cancer cells, thus contributing to immune evasion by engaging inhibitory NKG2A/CD94 receptors on NK cells and tumor-infiltrating T...
6.
Otero C, Petkova S, Ebermann M, Taher H, John N, Hoffmann K, et al.
bioRxiv . 2024 Mar; PMID: 38464092
Human cytomegalovirus (HCMV) encodes four viral Fc-gamma receptors (vFcγRs) that counteract antibody-mediated activation , but their role in infection and pathogenesis is unknown. To examine the function of vFcγRs in...
7.
Otero C, Barfield R, Scheef E, Nelson C, Rodgers N, Wang H, et al.
PLoS Pathog . 2023 Oct; 19(10):e1011378. PMID: 37871009
Cytomegalovirus (CMV) is the most common congenital infection and cause of birth defects worldwide. Primary CMV infection during pregnancy leads to a higher frequency of congenital CMV (cCMV) than maternal...
8.
Mostrom M, Yu S, Tran D, Saccoccio F, Versoza C, Malouli D, et al.
PLoS Pathog . 2023 Oct; 19(10):e1011646. PMID: 37796819
Congenital cytomegalovirus (cCMV) is the leading infectious cause of neurologic defects in newborns with particularly severe sequelae in the setting of primary CMV infection in the first trimester of pregnancy....
9.
Dirck A, Diggins N, Crawford L, Perez W, Parkins C, Struthers H, et al.
J Virol . 2023 Sep; 97(10):e0124123. PMID: 37772824
CD34 hematopoietic progenitor cells (HPCs) are an important cellular reservoir for latent human cytomegalovirus (HCMV). Several HCMV genes are expressed during latency that are involved with the maintenance of the...
10.
Wang H, Taher H, Kreklywich C, Schmidt K, Scheef E, Barfield R, et al.
bioRxiv . 2023 Jul; PMID: 37398229
One Sentence Summary: Congenital CMV transmission frequency in seronegative rhesus macaques is not affected by the deletion of the viral pentameric complex.