Daniel L Smith Jr
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Explore the profile of Daniel L Smith Jr including associated specialties, affiliations and a list of published articles.
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57
Citations
1493
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Recent Articles
11.
Austad S, Buford T, Allison D, Ballinger S, Brown A, Carter C, et al.
Geroscience
. 2021 Jul;
43(5):2149-2160.
PMID: 34304389
The UAB Nathan Shock Center focuses on comparative energetics and aging. Energetics, as defined for this purpose, encompasses the causes, mechanisms, and consequences of the acquisition, storage, and use of...
12.
Chakraborti A, Graham C, Chehade S, Vashi B, Umfress A, Kurup P, et al.
Front Neurosci
. 2021 Jun;
15:669410.
PMID: 34121997
The neurobiological mechanisms that mediate psychiatric comorbidities associated with metabolic disorders such as obesity, metabolic syndrome and diabetes remain obscure. High fructose corn syrup (HFCS) is widely used in beverages...
13.
Lee I, Kazamel M, McPherson T, McAdam J, Bamman M, Amara A, et al.
PLoS One
. 2021 May;
16(5):e0251087.
PMID: 33956876
Background/objective: Weight loss is a predictor of shorter survival in amyotrophic lateral sclerosis (ALS). We performed serial measures of body composition using Dual-energy X-ray Absorptiometry (DEXA) in ALS patients to...
14.
Enriquez-Hesles E, Smith Jr D, Maqani N, Wierman M, Sutcliffe M, Fine R, et al.
J Biol Chem
. 2020 Nov;
296:100125.
PMID: 33243834
Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging-associated diseases. In budding yeast,...
15.
Orlandella R, Turbitt W, Gibson J, Boi S, Li P, Smith Jr D, et al.
Cancers (Basel)
. 2020 Oct;
12(10).
PMID: 33036247
Although immune checkpoint inhibitors and targeted therapeutics have changed the landscape of treatment for renal cell carcinoma (RCC), most patients do not experience significant clinical benefits. Emerging preclinical studies report...
16.
Santos S, Laflin S, Broadway A, Burnet C, Hartheimer J, Rodgers J, et al.
Geroscience
. 2020 Oct;
43(2):941-964.
PMID: 33015753
Yeast cells survive in stationary phase culture by entering quiescence, which is measured by colony-forming capacity upon nutrient re-exposure. Yeast chronological lifespan (CLS) studies, employing the comprehensive collection of gene...
17.
Smith Jr D, Orlandella R, Allison D, Norian L
Geroscience
. 2020 Oct;
43(3):1123-1133.
PMID: 33006707
The field of aging research has grown rapidly over the last half-century, with advancement of scientific technologies to interrogate mechanisms underlying the benefit of life-extending interventions like calorie restriction (CR)....
18.
Miller R, Harrison D, Allison D, Bogue M, Debarba L, Diaz V, et al.
JCI Insight
. 2020 Sep;
5(21).
PMID: 32990681
Canagliflozin (Cana) is an FDA-approved diabetes drug that protects against cardiovascular and kidney diseases. It also inhibits the sodium glucose transporter 2 by blocking renal reuptake and intestinal absorption of...
19.
Deemer S, Davis R, Roberts B, Smith Jr D, Koutnik A, Poff A, et al.
Obesity (Silver Spring)
. 2020 Jul;
28(8):1447-1455.
PMID: 32618116
Objective: The aim of this study was to examine the effects of a ketone ester (KE)-supplemented diet on energy expenditure (EE) and adiposity in mice housed at 23 °C versus...
20.
Smith Jr D, Pavela G
Neurotox Res
. 2020 Mar;
38(1):242-248.
PMID: 32215816
Amyotrophic lateral sclerosis (ALS) is a devastating disease that like multiple other neurologic diseases has no curative treatment currently available. Environmental exposures to known neurotoxic compounds (e.g., pesticides, heavy metals,...