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Daniel J Sargent

Explore the profile of Daniel J Sargent including associated specialties, affiliations and a list of published articles. Areas
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Articles 293
Citations 19118
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Recent Articles
1.
Lawson T, Selva J, Carballo J, Caccamo M, Sargent D, Surbanovski N
Planta . 2025 Feb; 261(3):54. PMID: 39921711
This review discusses the DNA and RNA methylation pathways and their biological roles in Rosaceae developmental processes relevant for breeding and production. The Rosaceae is a plant family of great...
2.
Goldberg R, Sargent D, Morton R, Fuchs C, Ramanathan R, Williamson S, et al.
J Clin Oncol . 2023 Jun; 41(19):3461-3468. PMID: 37379691
Purpose: Three agents with differing mechanisms of action are available for treatment of advanced colorectal cancer: fluorouracil, irinotecan, and oxaliplatin. In this study, we compared the activity and toxicity of...
3.
Werner C, Gaynor R, Sargent D, Lillo A, Gorjanc G, Hickey J
Theor Appl Genet . 2023 Mar; 136(4):74. PMID: 36952013
For genomic selection in clonally propagated crops with diploid (-like) meiotic behavior to be effective, crossing parents should be selected based on genomic predicted cross-performance unless dominance is negligible. For...
4.
Qi X, Ogden E, Bostan H, Sargent D, Ward J, Gilbert J, et al.
Front Plant Sci . 2021 Jul; 12:692628. PMID: 34234801
Genotyping by sequencing approaches have been widely applied in major crops and are now being used in horticultural crops like berries and fruit trees. As the original and largest producer...
5.
Zaanan A, Shi Q, Taieb J, Alberts S, Meyers J, Smyrk T, et al.
JCO Precis Oncol . 2020 Sep; 4. PMID: 32923882
Purpose: The microsatellite instability (MSI) or deficient mismatch repair (dMMR) phenotype is usually regarded as a single biologic entity, given the absence of comparative analyses regarding prognosis and response to...
6.
An M, Tang J, Grothey A, Sargent D, Ou F, Mandrekar S
Contemp Clin Trials Commun . 2019 Dec; 17:100492. PMID: 31872158
Purpose: Missing data commonly occur in cancer clinical trials (CCT) and may hinder the search for alternative trial endpoints. We consider reasons for missing tumor measurement (TM) data in CCT...
7.
Sargent D, Buti M, Surbanovski N, Brurberg M, Alsheikh M, Kent M, et al.
PLoS One . 2019 Sep; 14(9):e0222829. PMID: 31536602
Strawberry powdery mildew (Podosphaera aphanis Wallr.) is a pathogen which infects the leaves, fruit, stolon and flowers of the cultivated strawberry (Fragaria ×ananassa), causing major yield losses, primarily through unmarketable...
8.
Major-Elechi B, Novotny P, Singh J, Bonner J, Dueck A, Sargent D, et al.
Int J Stat Med Res . 2019 Aug; 7(4):137-146. PMID: 31396297
Background: How can a clinician and patient incorporate survival and toxicity information into a single expression of comparative treatment benefit? Sloan . recently extended the ½ standard deviation concept for...
9.
Cockerton H, Li B, Vickerstaff R, Eyre C, Sargent D, Armitage A, et al.
Front Plant Sci . 2019 Aug; 10:924. PMID: 31379904
is a highly detrimental pathogen of soil cultivated strawberry (). Breeding of Verticillium wilt resistance into commercially viable strawberry cultivars can help mitigate the impact of the disease. In this...
10.
Du Y, Yin J, Sargent D, Mandrekar S
J Biopharm Stat . 2018 Nov; 29(2):271-286. PMID: 30403559
Phase I designs traditionally use the dose-limiting toxicity (DLT), a binary endpoint from the first treatment cycle, to identify the maximum-tolerated dose (MTD) assuming a monotonically increasing relationship between dose...